Department of Biomedical Medicine, Seoul National University Hospital, Seoul, Korea.
Department of Internal Medicine, Armed Forces Capital Hospital, Seoul, Korea.
Transplantation. 2021 Feb 1;105(2):404-412. doi: 10.1097/TP.0000000000003256.
Nationwide studies on the effects of wealth inequality on kidney transplantation are rare, particularly in a country with an expanded National Health Insurance Service and in Asian countries.
In this nationwide, population-based cohort study, we reviewed the national claims database of Korea in which details of nationwide health insurance are provided. From 2007 to 2015, 9 annual cohorts of end-stage renal disease patients were included. The annual financial statuses were collected and stratified into 5 subgroups in each year: the aided group in which insurance fee was waived and the 4 other groups divided by quartiles of their medical insurance fee. Time trends of incidence proportion of kidney transplantation among end-stage renal disease patients in each year were initially assessed. The risk of graft failure, both including death-censored graft failure and death with a functioning graft, was analyzed as a prognostic outcome within the transplant recipients.
Significant disparity in the accessibility of kidney transplantation was present, and it was further widening, particularly from 2009 in which the National Health Insurance Service started to cover desensitized kidney transplantation. Desensitized or preemptive transplantation was less common in the poorest group who were more frequently receiving transplantation after 5 years of dialysis in the latter years. The prognosis of kidney transplantation was significantly worse in the poorer people, and this disparity also worsened during the study period.
Prominent disparity regarding accessibility to and prognosis of kidney transplantation was observed in Korea according to wealth inequality, and this disparity was worsening.
关于财富不平等对肾移植影响的全国性研究很少,特别是在一个国家医疗保险服务扩大的国家和亚洲国家。
在这项全国性、基于人群的队列研究中,我们回顾了韩国国家索赔数据库,该数据库提供了全国医疗保险的详细信息。2007 年至 2015 年,纳入了 9 个年度终末期肾病患者队列。每年收集财务状况,并按每年的保险费分为 5 组:保险费豁免的援助组和其他 4 组按保险费四分位数划分。最初评估了每年终末期肾病患者肾移植发病率比例的时间趋势。在移植受者中,作为预后结果分析了移植物失功的风险,包括死亡相关移植物失功和带功能移植物的死亡。
肾移植的可及性存在显著差异,且差异进一步扩大,特别是自 2009 年国家健康保险服务开始覆盖脱敏肾移植以来。在较贫穷的群体中,脱敏或抢先移植的情况较少,这些人在后期接受透析治疗 5 年后更常接受移植。在较贫穷的人中,肾移植的预后明显较差,这种差异在研究期间也有所恶化。
根据财富不平等,韩国在肾移植的可及性和预后方面存在显著差异,且这种差异正在恶化。