Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA.
Clin J Am Soc Nephrol. 2011 Jul;6(7):1760-7. doi: 10.2215/CJN.08620910. Epub 2011 May 19.
Many factors have been shown to be associated with ESRD patient placement on the waiting list and receipt of kidney transplantation. Our study aim was to evaluate factors and assess the interplay of patient characteristics associated with progression to transplantation in a large cohort of referred patients from a single institution.
DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS: We examined 3029 consecutive adult patients referred for transplantation from 2003 to 2008. Uni- and multivariable logistic models were used to assess factors associated with progress to transplantation including receipt of evaluations, waiting list placement, and receipt of a transplant.
A total of 56%, 27%, and 17% of referred patients were evaluated, were placed on the waiting list, and received a transplant over the study period, respectively. Older age, lower median income, and noncommercial insurance were associated with decreased likelihood to ascend steps to receive a transplant. There was no difference in the proportion of evaluations between African Americans (57%) and Caucasians (56%). Age-adjusted differences in waiting list placement by race were attenuated with further adjustment for income and insurance. There was no difference in the likelihood of waiting list placement between African Americans and Caucasians with commercial insurance.
Race/ethnicity, age, insurance status, and income are predominant factors associated with patient progress to transplantation. Disparities by race/ethnicity may be largely explained by insurance status and income, potentially suggesting that variable insurance coverage exacerbates disparities in access to transplantation in the ESRD population, despite Medicare entitlement.
有许多因素与终末期肾病(ESRD)患者进入等待名单并接受肾移植有关。我们的研究目的是评估与患者特征相关的因素,并评估单一机构转诊患者中与向移植过渡相关的这些因素的相互作用。
设计、设置、参与者和测量:我们检查了 2003 年至 2008 年期间从单一机构转诊的 3029 例连续成年患者。使用单变量和多变量逻辑模型评估与向移植过渡相关的因素,包括接受评估、等待名单安置和接受移植。
在研究期间,共有 56%、27%和 17%的转诊患者接受了评估、被安置在等待名单上并接受了移植。年龄较大、中等收入较低和非商业保险与接受移植的可能性降低有关。非裔美国人(57%)和白人(56%)之间接受评估的比例没有差异。在考虑收入和保险后,种族对等待名单安置的年龄调整差异减弱。有商业保险的非裔美国人和白人在等待名单安置上的可能性没有差异。
种族/民族、年龄、保险状况和收入是与患者向移植过渡相关的主要因素。种族/民族的差异可能主要由保险状况和收入解释,这可能表明在 ESRD 人群中,医疗保险覆盖范围的差异可能会加剧获得移植的机会不均等,尽管有医疗保险的资格。