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全球精神障碍患者治疗预算的有效性——基于德国13项对照研究索赔数据的荟萃分析

Effectiveness of Global Treatment Budgets for Patients With Mental Disorders-Claims Data Based Meta-Analysis of 13 Controlled Studies From Germany.

作者信息

Baum Fabian, Schoffer Olaf, Neumann Anne, Seifert Martin, Kliemt Roman, March Stefanie, Swart Enno, Häckl Dennis, Pfennig Andrea, Schmitt Jochen

机构信息

Center of Evidence-Based Health Care, Medizinische Fakultät Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.

WIG2 Scientific Institute for Health Economics and Health System Research, Leipzig, Germany.

出版信息

Front Psychiatry. 2020 Mar 24;11:131. doi: 10.3389/fpsyt.2020.00131. eCollection 2020.

Abstract

Individuals with mental disorders need continuous and efficient collaboration between different sectors of care. In 2012, a new law in Germany enabled the implementation of novel budgets in psychiatry (flexible and integrated treatment = FIT). Hospitals implementing FIT programs have been evaluated in controlled cohort studies. We present first results based on a meta-analysis from 13 FIT hospitals. We undertook a series of claims-data-based controlled cohort studies. Data from over 70 statutory health insurance (SHI) funds in Germany were analyzed. All patients insured by any of the participating SHI funds and treated in one of the FIT hospitals for any of 16 predefined mental disorders were compared with matched control patients from routine care. The patient collective was subdivided into hospital-new and hospital-known patients. Analyses included utilization of inpatient care, day care, outpatient PIA (psychiatrische Institutsambulanz) care, outpatient care with established practitioners, and durations of sick leave. Individual treatment effects of the 13 FIT hospitals were pooled in a random-effects meta-analysis. Meta-regression analysis was used to explore potential reasons for heterogeneity in model effectiveness. The meta-analysis revealed a significant reduction by over 5 days of inpatient care in hospital-new patients in FIT hospitals compared to control hospitals. This effect was stronger among FIT hospitals with a preexisting FIT-like environment. There was no overall significant effect regarding sick leave between the two groups. Further meta-regression for hospital-new patients revealed a significantly reduced duration of sick leave by almost 13 days for patients in FIT hospitals with a preexisting FIT-like contract compared to FIT hospitals without such a contract. This study suggests positive effects of FIT programs for patients with mental disorders pointing toward a shorter duration of inpatient treatment. Furthermore, contracts already existent prior to initialization of FIT programs appear to have facilitated the transition into the new treatment environment. For FIT hospitals without such contracts, supposedly there is a certain implementation phase for effects to be apparent. The results should still be interpreted with caution as this manuscript only covers the first year of the 5 year evaluation period in 13 of 18 FIT hospitals. This study was registered in the database "Health Services Research Germany" (trial number: VVfD_EVA64_15_003713).

摘要

患有精神障碍的个体需要不同护理部门之间持续且高效的协作。2012年,德国一项新法律使得在精神病学领域实施新预算(灵活综合治疗 = FIT)成为可能。实施FIT项目的医院已在对照队列研究中得到评估。我们基于对13家FIT医院的荟萃分析给出了初步结果。我们开展了一系列基于理赔数据的对照队列研究。分析了来自德国70多家法定健康保险(SHI)基金的数据。将任何参与SHI基金承保且在13家FIT医院之一接受治疗的、患有16种预定义精神障碍中任何一种的所有患者,与来自常规护理的匹配对照患者进行比较。患者群体被细分为新入院患者和复诊患者。分析内容包括住院护理、日间护理、门诊PIA(精神病院门诊)护理、与执业医师的门诊护理的使用情况以及病假时长。对13家FIT医院的个体治疗效果进行随机效应荟萃分析汇总。采用荟萃回归分析来探究模型有效性异质性的潜在原因。荟萃分析显示,与对照医院相比,FIT医院的新入院患者住院护理天数显著减少超过5天。在已存在类似FIT环境的FIT医院中,这种效果更强。两组之间病假方面没有总体显著影响。对新入院患者的进一步荟萃回归显示,与没有此类合同的FIT医院相比,有预先存在类似FIT合同的FIT医院的患者病假时长显著减少近13天。这项研究表明FIT项目对精神障碍患者有积极影响,住院治疗时长更短。此外,在FIT项目启动之前就已存在的合同似乎促进了向新治疗环境的过渡。对于没有此类合同的FIT医院,可能需要一定的实施阶段效果才会显现。由于本手稿仅涵盖18家FIT医院中13家在5年评估期的第一年情况,结果仍应谨慎解读。本研究已在“德国卫生服务研究”数据库中注册(试验编号:VVfD_EVA64_15_003713)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bce/7105704/2ead3ababfbd/fpsyt-11-00131-g0001.jpg

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