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运动通过非编码RNA介导心脏保护作用。

Exercise Mediates Heart Protection via Non-coding RNAs.

作者信息

Zhang Yuelin, He Nana, Feng Beili, Ye Honghua

机构信息

Department of Cardiology, HwaMei Hospital, University of Chinese Academy of Sciences, Ningbo, China.

Ningbo Institute of Life and Health Industry, University of Chinese Academy of Sciences, Ningbo, China.

出版信息

Front Cell Dev Biol. 2020 Mar 20;8:182. doi: 10.3389/fcell.2020.00182. eCollection 2020.

Abstract

Cardiovascular diseases (CVDs) have become the central matter of death worldwide and have emerged as a notable concern in the healthcare field. There is accumulating evidence that regular exercise training can be as a reliable and widely favorable approach to prevent the heart from cardiovascular events. Non-coding RNAs (ncRNAs) could act as innovative biomarkers and auspicious therapeutic targets to reduce the incidence of CVDs. In this review, we summarized the regulatory effects of ncRNAs in the cardiac-protection provided by exercise to assess potential therapies for CVDs and disease prevention.

摘要

心血管疾病(CVDs)已成为全球死亡的核心问题,并在医疗保健领域成为一个显著的关注点。越来越多的证据表明,定期运动训练可以作为一种可靠且广泛适用的方法来预防心脏发生心血管事件。非编码RNA(ncRNAs)可以作为创新的生物标志物和良好的治疗靶点,以降低心血管疾病的发病率。在本综述中,我们总结了ncRNAs在运动提供的心脏保护中的调节作用,以评估心血管疾病的潜在治疗方法和疾病预防措施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5ef/7098911/ac0a781a02a1/fcell-08-00182-g001.jpg

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