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急性缺血性脑血管卒中患者新发心房颤动的发生率

Frequency of de novo atrial fibrillation in patients presenting with acute ischemic cerebrovascular stroke.

作者信息

Abdelnabi Mahmoud, Almaghraby Abdallah, Saleh Yehia, Özden Tok Özge, Kemaloğlu Öz Tuğba, Abdelkarim Ola, Badran Haitham

机构信息

Cardiology and Angiology Unit, Department of Clinical and Experimental Internal Medicine, Medical Research Institute, Alexandria University, Alexandria, Egypt.

Department of Cardiology, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

出版信息

Egypt Heart J. 2020 Apr 7;72(1):18. doi: 10.1186/s43044-020-00050-8.

Abstract

BACKGROUND

Atrial fibrillation (AF) affects millions of people worldwide and can remain undiagnosed for years. It is a major cause of cerebrovascular stroke (CVS); hence, early detection is extremely important in order to decrease the risk of CVS. We conducted a retrospective observational study looking into the prevalence of silent AF in 3299 patients admitted from January 2014 to December 2017 in a tertiary care stroke specialized center. Ischemic CVS was confirmed either by using multislice computed tomography (MSCT) or magnetic resonance imaging (MRI) of the brain. AF was diagnosed by electrocardiography (ECG) at the time of admission or during the hospital stay. Patients with a history of AF were excluded from the study.

RESULTS

Of the 3299 patients admitted by acute ischemic CVS, 707 (21.43%) had a history of AF and thus were excluded from the study. Of the remaining 2592 patients eligible for the study, 1666 (64.27%) were males with a mean age of 56.06 years (± 16.01). A total of 2313 (89.24%) patients remained in sinus rhythm throughout the hospital stay, 211 (8.14%) patients were in AF on admission, and 68 (2.62 %) patients developed AF during their hospital stay. The total number of newly diagnosed patients with AF was 279 (10.76%).

CONCLUSION

The prevalence of de novo atrial fibrillation in patients presented with acute cerebrovascular stroke is high. The implementation of good screening programs can significantly reduce the risk of disabilities and morbidities.

摘要

背景

心房颤动(AF)在全球影响着数百万人,且可能多年未被诊断出来。它是脑血管性卒中(CVS)的主要原因;因此,为降低CVS风险,早期检测极为重要。我们进行了一项回顾性观察研究,调查2014年1月至2017年12月在一家三级护理卒中专科医院收治的3299例患者中无症状性AF的患病率。通过使用脑部多层计算机断层扫描(MSCT)或磁共振成像(MRI)确诊缺血性CVS。通过入院时或住院期间的心电图(ECG)诊断AF。有AF病史的患者被排除在研究之外。

结果

在3299例急性缺血性CVS患者中,707例(21.43%)有AF病史,因此被排除在研究之外。在其余2592例符合研究条件的患者中,1666例(64.27%)为男性,平均年龄56.06岁(±16.01)。共有2313例(89.24%)患者在住院期间一直处于窦性心律,211例(8.14%)患者入院时为AF,68例(2.62%)患者在住院期间发生AF。新诊断为AF的患者总数为279例(10.76%)。

结论

急性脑血管性卒中患者中初发性心房颤动的患病率较高。实施良好的筛查计划可显著降低残疾和发病风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff43/7138879/c7a192aa88a1/43044_2020_50_Fig1_HTML.jpg

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