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化脓性汗腺炎患者手术治疗中的术前超声规划

Pre-operative ultrasound planning in the surgical management of patients with hidradenitis suppurativa.

作者信息

Cuenca-Barrales C, Salvador-Rodríguez L, Arias-Santiago S, Molina-Leyva A

机构信息

Instituto de Investigación Biosanitaria, Ibs Granada, Granada, Spain.

Hidradenitis Suppurativa Clinic, Dermatology Department, Hospital Universitario Virgen de las Nieves, Granada, Spain.

出版信息

J Eur Acad Dermatol Venereol. 2020 Oct;34(10):2362-2367. doi: 10.1111/jdv.16435. Epub 2020 Jul 13.

Abstract

BACKGROUND

Ultrasonography can improve disease severity assessment in hidradenitis suppurativa (HS) patients. The use of pre-operative ultrasonography could improve surgical outcomes in HS patients.

OBJECTIVES

(i) To assess changes in the projected skin-excised area after the use of pre-operative ultrasonography, (ii) to explore the clinical factors potentially associated with inaccurate clinical surgical delimitation and (iii) to compare recurrence rates after pre-operative ultrasound vs clinical surgical margin delimitation at week 24.

METHODS

Cohort study. Patient candidates for surgical treatment by wide excision and healing by secondary intention with a clinical projected skin-excised area equal to or larger than 15 cm were included. The main variables of interest were the clinical and ultrasound projected skin-excised area and surgical recurrence.

RESULTS

Pre-operative ultrasound surgical margin delimitation increased the mean excised area by 3.67 (SD 0.86) cm , P = 0.004. The Bland-Altman plot showed that in 65% of surgical procedures the use of ultrasonography increased the projected skin-excised area. Higher IHS4 scores, BMI, male sex and Hurley stage II vs III all increased the difference between clinical and ultrasound surgical delimitation. At week 24, the recurrence rate in the surgical clinical delimitation cohort was 30% compared to 10% in the cohort with pre-operative ultrasonography (P = 0.10).

CONCLUSIONS

Pre-operative ultrasonography improves surgical margin delimitation and can lower recurrence rates at 24 weeks in HS patients. Potential risk factors for inaccurate clinical surgical delimitation are obesity, male sex, Hurley II stage and elevated IHS4 scores, so special attention should be given to these patients when ultrasonography is not available and surgical delimitation is based only on clinical examination.

摘要

背景

超声检查可改善化脓性汗腺炎(HS)患者的疾病严重程度评估。术前超声检查的应用可改善HS患者的手术效果。

目的

(i)评估术前超声检查后预计切除皮肤面积的变化,(ii)探讨可能与临床手术界限划定不准确相关的临床因素,以及(iii)比较术前超声检查与临床手术切缘划定在第24周时的复发率。

方法

队列研究。纳入临床预计切除皮肤面积等于或大于15平方厘米、拟通过广泛切除并二期愈合进行手术治疗的患者。主要关注变量为临床和超声预计切除皮肤面积及手术复发情况。

结果

术前超声手术切缘划定使平均切除面积增加了3.67(标准差0.86)平方厘米,P = 0.004。Bland-Altman图显示,在65%的手术中,超声检查的使用增加了预计切除皮肤面积。较高的IHS4评分、体重指数、男性性别以及Hurley II期与III期相比,均增加了临床与超声手术界限划定之间的差异。在第24周时,手术临床界限划定队列的复发率为30%,而术前超声检查队列的复发率为10%(P = 0.10)。

结论

术前超声检查可改善手术切缘划定,并可降低HS患者24周时的复发率。临床手术界限划定不准确的潜在风险因素为肥胖、男性性别、Hurley II期以及IHS4评分升高,因此在无法进行超声检查且手术界限划定仅基于临床检查时,应特别关注这些患者。

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