Michelucci Alessandra, Janowska Agata, Granieri Giammarco, Margiotta Flavia M, Morganti Riccardo, Romanelli Marco, Dini Valentina
Department of Dermatology University of Pisa Pisa Italy.
Statistical Support to Clinical Trials Department University of Pisa Pisa Italy.
Health Sci Rep. 2023 Oct 9;6(10):e1582. doi: 10.1002/hsr2.1582. eCollection 2023 Oct.
The most appropriate management of recurrent Hidradenitis Suppurativa (HS) lesions consists of wide surgical removal of the lesions with subsequent healing by second intention. Successful wound healing depends on the choice of an adequate wound dressing, targeted to the features of the wound.We enrolled 25 patients randomized into three groups according to the advanced dressing used in second intention healing of postsurgical wounds (standard therapy, an oxygen-enriched oil-based medical device with prolonged release of reactive oxygen species [ROS], ultra-portable negative pressure therapy). Data on wound size, clinical appearance of the wound bed, and pain experienced by the patient were collected twice a week for 4 weeksNo statistically significant differences were observed between the different groups evaluated. Oxygen-enriched oil-based medical device with prolonged release of ROS can be included in the principle of HS-tissue, inflammation, moisture, and epithelium (TIME).
复发性化脓性汗腺炎（HS）病变的最恰当处理方法是广泛手术切除病变，随后让伤口通过二期愈合实现愈合。成功的伤口愈合取决于根据伤口特点选择合适的伤口敷料。我们纳入了25例患者，根据用于手术伤口二期愈合的先进敷料（标准治疗、具有活性氧[ROS]长效释放功能的富氧油基医疗器械、超便携式负压治疗）将其随机分为三组。每周两次收集伤口大小、伤口床临床表现及患者疼痛情况的数据，持续4周。在评估的不同组之间未观察到统计学上的显著差异。具有ROS长效释放功能的富氧油基医疗器械可纳入HS组织、炎症、湿度和上皮（TIME）原则。
