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中国东北沈阳社区药房无处方配发治疗普通感冒相关急性咳嗽的抗生素:一项横断面研究

Dispensing Antibiotics without a Prescription for Acute Cough Associated with Common Cold at Community Pharmacies in Shenyang, Northeastern China: A Cross-Sectional Study.

作者信息

Shi Li, Chang Jie, Liu Xiaoxi, Zhai Panpan, Hu Shuchen, Li Pengchao, Hayat Khezar, Kabba John Alimamy, Feng Zhitong, Yang Caijun, Jiang Minghuan, Zhao Mingyue, Hu Hao, Fang Yu

机构信息

Department of Pharmacy Administration and Clinical Pharmacy, School of Pharmacy, Xi'an Jiaotong University, Xi'an 710061, China.

Center for Drug Safety and Policy Research, Xi'an Jiaotong University, Xi'an 710061, China.

出版信息

Antibiotics (Basel). 2020 Apr 6;9(4):163. doi: 10.3390/antibiotics9040163.

Abstract

The inappropriate use of antibiotics is a major health issue in China. We aimed to assess nonprescription antibiotic dispensing and assess pharmacy service practice at community pharmacies in Shenyang, northeastern China, and to compare these practices between pediatric and adult cases. A cross-sectional study was performed from March to May 2018 using the standardized client method. Two different simulated scenarios were presented at pharmacies, namely, pediatric and adult acute cough associated with a common cold. Of 150 pharmacy visits, 147 visits were completed (pediatric case: 73, adult case: 74). A total of 130 (88.4%) community pharmacies dispensed antibiotics without a prescription, with a significant difference between pediatric and adult cases (pediatric case, 79.5% versus adult case, 97.3%, p = 0.005). Symptoms were asked in most visits (pediatric case: 82.2%, adult case 82.4%). Patients' previous treatment and history of allergies were both inquired more frequently in the pediatric cases than in the adult cases. Medication advice was provided more often in the adult cases than in pediatric cases. Antibiotics were easily obtained without a prescription in Shenyang, especially for adult patients. Adequate inquiries and counseling had not occurred in most pharmacies.

摘要

抗生素的不当使用是中国的一个重大健康问题。我们旨在评估非处方抗生素配药情况,并评估中国东北沈阳社区药房的药学服务实践,同时比较儿科和成人病例的这些实践情况。2018年3月至5月采用标准化顾客方法进行了一项横断面研究。在药房呈现了两种不同的模拟场景,即与普通感冒相关的儿科和成人急性咳嗽。在150次药房就诊中,完成了147次(儿科病例:73次,成人病例:74次)。共有130家(88.4%)社区药房在无处方的情况下配发抗生素,儿科和成人病例之间存在显著差异(儿科病例为79.5%,成人病例为97.3%,p = 0.005)。在大多数就诊中询问了症状(儿科病例:82.2%,成人病例82.4%)。儿科病例中询问患者既往治疗情况和过敏史的频率均高于成人病例。成人病例中提供用药建议的频率高于儿科病例。在沈阳,无处方很容易获得抗生素,尤其是对于成年患者。大多数药房没有进行充分的询问和咨询。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8b6e/7235837/2f428e0bff1f/antibiotics-09-00163-g0A1.jpg

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