Science and technology department, China Pharmaceutical University, Nanjing, People's Republic of China.
Research Center of Biostatistics and Computational Pharmacy, China Pharmaceutical University, Nanjing, People's Republic of China.
BMC Anesthesiol. 2020 Apr 8;20(1):82. doi: 10.1186/s12871-020-00997-w.
Difficult tracheal intubation is a common problem encountered by anesthesiologists in the clinic. This study was conducted to assess the difficulty of tracheal intubation in infants with Pierre Robin syndrome (PRS) by incorporating computed tomography (CT) to guide airway management for anesthesia.
In this retrospective study, we analyzed case-level clinical data and CT images of 96 infants with PRS. First, a clinically experienced physician labeled CT images, after which the color space conversion, binarization, contour acquisition, and area calculation processing were performed on the annotated files. Finally, the correlation coefficient between the seven clinical factors and tracheal intubation difficulty, as well as the differences in each risk factor under tracheal intubation difficulty were calculated.
The absolute value of the correlation coefficient between the throat area and tracheal intubation difficulty was 0.54; the observed difference was statistically significant. Body surface area, weight, and gender also showed significant difference under tracheal intubation difficulty.
There is a significant correlation between throat area and tracheal intubation difficulty in infants with PRS. Body surface area, weight and gender may have an impact on tracheal intubation difficulty in infants with PRS.
困难气管插管是临床麻醉医师常见的问题。本研究旨在通过计算机断层扫描(CT)指导气道管理来评估Pierre Robin 综合征(PRS)婴儿的气管插管难度。
本回顾性研究分析了 96 例 PRS 婴儿的病例水平临床数据和 CT 图像。首先,一位临床经验丰富的医生对 CT 图像进行标注,然后对标注文件进行颜色空间转换、二值化、轮廓获取和面积计算处理。最后,计算了 7 个临床因素与气管插管困难的相关系数,以及每个危险因素在气管插管困难下的差异。
喉面积与气管插管困难的相关系数绝对值为 0.54;观察到的差异具有统计学意义。体表面积、体重和性别在气管插管困难下也存在显著差异。
PRS 婴儿的喉面积与气管插管困难程度存在显著相关性。体表面积、体重和性别可能会影响 PRS 婴儿的气管插管困难程度。