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干燥综合征和慢性炎症性脱髓鞘性多发性神经病患者中罕见的磷脂酶A2受体阳性膜性肾病

Rare Occurrence of PLA2R-Positive Membranous Nephropathy in a Patient with Sjogren's Syndrome and CIDP.

作者信息

Gupta Nimish, Khullar Dinesh, Prasad Pallavi, Grover Rahul, Chabbra Gagandeep, Gandhi Kunal Raj, Bagai Sahil

机构信息

Department of Nephrology and Renal Transplant, Max Superspeciality Hospital, New Delhi, India.

出版信息

Indian J Nephrol. 2020 Mar-Apr;30(2):117-120. doi: 10.4103/ijn.IJN_152_19. Epub 2020 Jan 3.

DOI:10.4103/ijn.IJN_152_19
PMID:32269437
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7132851/
Abstract

Membranous nephropathy is known to be associated with number of autoimmune diseases. Occurrence of PLA2R positive membranous nephropathy with sjogren's syndrome and chronic inflammatory demyelinating neuropathy (CIDP) is quite rare. Role of PLA2R antigen in autoimmune diseases like sjogren's syndrome and CIDP is largely unknown. Choice and initiation of immunosuppression if required may also be governed by the presence of other autoimmune diseases along with PLA2R positive membranous nephropathy.

摘要

已知膜性肾病与多种自身免疫性疾病相关。伴有干燥综合征和慢性炎症性脱髓鞘性多发性神经病（CIDP）的PLA2R阳性膜性肾病的发生相当罕见。PLA2R抗原在干燥综合征和CIDP等自身免疫性疾病中的作用在很大程度上尚不清楚。如果需要，免疫抑制的选择和启动也可能受PLA2R阳性膜性肾病伴其他自身免疫性疾病的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/7336e912f75f/IJN-30-117-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/506a729e8a33/IJN-30-117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/76d5621fb3a1/IJN-30-117-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/baf6148d55a1/IJN-30-117-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/4ab2ac0ac6b4/IJN-30-117-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/7336e912f75f/IJN-30-117-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/506a729e8a33/IJN-30-117-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/76d5621fb3a1/IJN-30-117-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/baf6148d55a1/IJN-30-117-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/4ab2ac0ac6b4/IJN-30-117-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c53c/7132851/7336e912f75f/IJN-30-117-g005.jpg

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2
Anti-PLA2R antibody in a secondary cause of membranous nephropathy.抗磷脂酶A2受体抗体在膜性肾病的继发原因中。
Nephrology (Carlton). 2018 Jan;23(1):94-95. doi: 10.1111/nep.12997.
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Primary Membranous Nephropathy.
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BMC Med. 2017 Mar 31;15(1):69. doi: 10.1186/s12916-017-0837-1.
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