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丝绸衣物疗法对特应性皮炎患者的影响。

Influence of silk clothing therapy in patients with atopic dermatitis.

作者信息

Hung Min-Hsung, Sartika Dewi, Chang Shu-Jen, Chen Shyi-Jou, Wang Chih-Chien, Hung Yi-Jen, Cherng Juin-Hong, Chiu Yaw-Kwan

机构信息

Department of Pediatrics, Songshan Branch, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan, R.O.C.

Department and Graduate Institute of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan, R.O.C.

出版信息

Dermatol Reports. 2019 Dec 22;11(2):8176. doi: 10.4081/dr.2019.8176. eCollection 2019 Sep 19.

DOI:10.4081/dr.2019.8176
PMID:32269744
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7137929/
Abstract

The existence of red, inflammatory, and chronic itchy condition in the skin is commonly speculated as the presence of Atopic Dermatitis (AD) in patients. The use of silk clothing as a non-pharmacological approach in the management of AD has been noticed as an effective alternative therapy; however, the evidence based on its usage is poorly served. Hence, we aim to evaluate the effectiveness of using pure silk clothing in the therapy of AD patients. The clinical trial was performed by recruiting 30 patients with AD for up to 8 weeks of observation. They were instructed to wear pure silk clothing for the whole day without any additional medication and were investigated using the AD-related questionnaires. The findings revealed a significant decrease of AD occurrence along with a great improvement of patient's quality of life at each time point. Our investigation demonstrated that this treatment promotes good skin appearance, comfort, and remarkable improvement in the quality of life. This promising preliminary outcome warrants a further study; hence, it can be a potential non-pharmacological treatment choice for controlling the severity of AD.

摘要

皮肤出现红色、炎症性和慢性瘙痒状况通常被推测为患者患有特应性皮炎(AD)。丝绸衣物作为一种非药物方法用于AD的管理已被视为一种有效的替代疗法;然而,基于其使用的证据并不充分。因此,我们旨在评估使用纯丝绸衣物治疗AD患者的有效性。该临床试验通过招募30名AD患者进行长达8周的观察。他们被指示全天穿着纯丝绸衣物,不使用任何额外药物,并使用与AD相关的问卷进行调查。研究结果显示,在每个时间点,AD的发生率显著降低,患者的生活质量有了很大改善。我们的调查表明,这种治疗能促进良好的皮肤外观、舒适度,并显著改善生活质量。这一有前景的初步结果值得进一步研究;因此,它可能是控制AD严重程度的一种潜在非药物治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/dc71a4698cbd/dr-11-2-8176-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/fe7968440f8f/dr-11-2-8176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/ff2b64bcd7c6/dr-11-2-8176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/d29f55d6ca9d/dr-11-2-8176-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/b9087959cdd7/dr-11-2-8176-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/dc71a4698cbd/dr-11-2-8176-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/fe7968440f8f/dr-11-2-8176-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/ff2b64bcd7c6/dr-11-2-8176-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/d29f55d6ca9d/dr-11-2-8176-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/b9087959cdd7/dr-11-2-8176-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7d0e/7137929/dc71a4698cbd/dr-11-2-8176-g005.jpg

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本文引用的文献

1
Silk garments plus standard care compared with standard care for treating eczema in children: A randomised, controlled, observer-blind, pragmatic trial (CLOTHES Trial).丝绸衣物加标准护理与标准护理治疗儿童湿疹的比较:一项随机、对照、观察者盲法、实用性试验(衣物试验)。
PLoS Med. 2017 Apr 11;14(4):e1002280. doi: 10.1371/journal.pmed.1002280. eCollection 2017 Apr.
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Atopic dermatitis: Burden of illness, quality of life, and associated complications.特应性皮炎:疾病负担、生活质量及相关并发症
Allergy Asthma Proc. 2017 Jan 1;38(1):3-8. doi: 10.2500/aap.2017.38.4005.
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Therapies to improve the cosmetic symptoms of atopic dermatitis.
改善特应性皮炎皮肤症状的疗法。
Cutis. 2016 Mar;97(3):183-6.
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Acid-coated Textiles (pH 5.5-6.5)--a New Therapeutic Strategy for Atopic Eczema?酸性涂层纺织品(pH值5.5 - 6.5)——特应性皮炎的一种新治疗策略?
Acta Derm Venereol. 2015 Jul;95(6):659-63. doi: 10.2340/00015555-1916.
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Superantigens in dermatology.皮肤科中的超抗原。
J Am Acad Dermatol. 2011 Mar;64(3):455-72; quiz 473-4. doi: 10.1016/j.jaad.2010.03.044.
6
Staphylococcal-mediated worsening of atopic dermatitis: many players involved.葡萄球菌介导的特应性皮炎恶化:涉及众多因素。
Br J Dermatol. 2010 Dec;163(6):1147. doi: 10.1111/j.1365-2133.2010.10114.x.
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Use of a silklike bedding fabric in patients with atopic dermatitis.在特应性皮炎患者中使用丝样床上用品织物。
Pediatr Dermatol. 2008 Jul-Aug;25(4):439-43. doi: 10.1111/j.1525-1470.2008.00717.x.
8
Action of a silk fabric treated with AEGIS in children with atopic dermatitis: a 3-month trial.经AEGIS处理的丝绸织物对特应性皮炎患儿的作用:一项为期3个月的试验。
Pediatr Allergy Immunol. 2007 Jun;18(4):335-8. doi: 10.1111/j.1399-3038.2006.00511.x. Epub 2007 Mar 7.
9
Diagnosis and treatment of atopic dermatitis in children and adults: European Academy of Allergology and Clinical Immunology/American Academy of Allergy, Asthma and Immunology/PRACTALL Consensus Report.儿童和成人特应性皮炎的诊断与治疗:欧洲变态反应和临床免疫学会/美国变态反应、哮喘与免疫学会/PRACTALL共识报告
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Coated textiles in the treatment of atopic dermatitis.涂层纺织品在特应性皮炎治疗中的应用
Curr Probl Dermatol. 2006;33:144-51. doi: 10.1159/000093941.