杜氏肌营养不良症：问题的核心
Duchenne Muscular Dystrophy: the Heart of the Matter.
作者信息
Shih Jeffrey A, Folch Alejandro, Wong Brenda L
机构信息
University of Massachusetts, 55 Lake Avenue North, Worcester, MA, 01532, USA.
出版信息
Curr Heart Fail Rep. 2020 Jun;17(3):57-66. doi: 10.1007/s11897-020-00456-0.
PURPOSE OF REVIEW
Duchenne muscular dystrophy is one of many neuromuscular disorders, but it frequently causes severe disability early in life and early death. Cardiac involvement is an important cause of morbidity and mortality.
RECENT FINDINGS
Heart disease in Duchenne muscular dystrophy can include a cardiomyopathy leading to end-stage heart failure along with associated supraventricular and ventricular arrhythmias. This article reviews the diagnosis and treatment of heart disease in Duchenne muscular dystrophy as well as emerging therapies.
综述目的
杜氏肌营养不良症是众多神经肌肉疾病之一，但它常常在生命早期导致严重残疾和过早死亡。心脏受累是发病和死亡的重要原因。
最新发现
杜氏肌营养不良症中的心脏病可包括导致终末期心力衰竭的心肌病以及相关的室上性和室性心律失常。本文综述了杜氏肌营养不良症中心脏病的诊断和治疗以及新兴疗法。
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