Toselli Marco, Bosi Davide, Benatti Giorgio, Solinas Emilia, Cattabiani Maria Alberta, Vignali Luigi
Azienda Ospedaliera-Universitaria di Parma - Interventional Cardiology Unit, Viale Gramsci 14, 43126, Parma, Italy.
J Thromb Thrombolysis. 2020 Oct;50(3):668-673. doi: 10.1007/s11239-020-02097-5.
Atrial fibrillation is the most common cardiac arrhythmia and is a major cause of embolic stroke. In patients at high bleeding risk such as those with hemophilia, the thromboembolic prevention is challenging. We herein present three patients affected by moderate to severe hemophilia and atrial fibrillation that were treated in our Institution between March 2018 and September 2019, with percutaneous left atrial appendage closure. In patients with relative or absolute contraindications to long-term anticoagulant therapy, the left atrial appendage closure could represent a reasonable strategy.
心房颤动是最常见的心律失常，也是栓塞性中风的主要原因。在血友病等出血风险高的患者中，预防血栓栓塞具有挑战性。我们在此介绍2018年3月至2019年9月期间在我们机构接受经皮左心耳封堵治疗的3例中重度血友病合并心房颤动患者。对于长期抗凝治疗有相对或绝对禁忌证的患者，左心耳封堵可能是一种合理的策略。
