Department of Cardiology, Tokyo Metropolitan Hiroo Hospital, Tokyo, Japan.
Tokyo Metropolitan Health and Medical Treatment Corporation Ohkubo Hospital, Tokyo, Japan.
J Cardiovasc Electrophysiol. 2020 Jun;31(6):1298-1306. doi: 10.1111/jce.14485. Epub 2020 Apr 20.
This study aimed to compare touch-up ablation (TUA) rates and pulmonary vein isolation (PVI) durability of hot balloon ablation (HBA) and cryoballoon ablation (CBA) in paroxysmal atrial fibrillation (PAF) patients.
In total, 137 PAF patients were enrolled in the study. Among them, 59 underwent two HBA procedures at 6-month intervals and 78 patients underwent two CBA sessions, both regardless of atrial fibrillation recurrence. Propensity score matching was performed to estimate similar patient characteristics between the HBA and CBA groups.
Each group comprised of 46 matched patients for comparison. The TUA rate at the first session was higher for HBA (49 of 184 PVs) than for CBA (20 PVs) (P = .01), with the highest incidence at the left superior pulmonary vein (LSPV). The rates of PVI durability at the second session performed 7 months later were similar between HBA (168 of 184 PVs) and CBA (162 PVs) groups. The PVI durability rate at the TUA sites of the first session was higher for HBA than for CBA (41 of 49 PVs vs 10 PVs, respectively; P = .01). Fifty percent of the patients underwent HBA at 73°C for the LSPV. HBA performed at 73°C yielded a lower TUA rate than that at 70°C (16 of 23 PVs vs 7 of 23 PVs; P = .008).
While PVI durability was similar between HBA and CBA, the TUA rate was higher for HBA than for CBA, especially on the LSPV. For LSPV, HBA at a balloon temperature of 73°C may reduce the TUA rate.
本研究旨在比较阵发性心房颤动(PAF)患者中热球囊消融(HBA)和冷冻球囊消融(CBA)的补点消融(TUA)率和肺静脉隔离(PVI)持久性。
本研究共纳入 137 例 PAF 患者。其中,59 例行 2 次 HBA 治疗,间隔 6 个月;78 例行 2 次 CBA 治疗,均不考虑房颤复发。采用倾向评分匹配法估计 HBA 和 CBA 组患者的相似特征。
每组各有 46 例匹配患者进行比较。第一次治疗时,HBA 的 TUA 率(184 个 PV 中有 49 个)高于 CBA(20 个 PV)(P=0.01),左肺上静脉(LSPV)发生率最高。7 个月后进行的第二次治疗中,HBA(184 个 PV 中有 168 个)和 CBA(162 个 PV)组的 PVI 持久性相似。第一次治疗的 TUA 部位的 PVI 持久性率,HBA 高于 CBA(分别为 49 个 PV 中有 41 个和 10 个 PV;P=0.01)。50%的 HBA 患者行 LSPV 73°C消融。73°C 的 HBA 消融比 70°C 的 TUA 率低(23 个 PV 中有 16 个和 23 个 PV 中有 7 个;P=0.008)。
虽然 HBA 和 CBA 的 PVI 持久性相似,但 HBA 的 TUA 率高于 CBA,尤其是在 LSPV。对于 LSPV,73°C 球囊温度的 HBA 可能会降低 TUA 率。