Unit of Vascular Surgery, Fondazione Policlinico Universitario A. Gemelli - IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.
Eur Rev Med Pharmacol Sci. 2020 Mar;24(6):3274-3281. doi: 10.26355/eurrev_202003_20695.
This study aims to analyze the early and late outcomes of our 30-year experience with mycotic aneurysms of the abdominal aorta and iliac arteries.
This retrospective cohort study compared the outcomes of all the patients with mycotic aneurysm, by analyzing prospectively collected data between September 1989 and October 2019 from the Unit of Vascular Surgery of Fondazione Policlinico Universitario Gemelli - IRCCS in Rome, Italy.
Twenty-three patients with mycotic aneurysm were included. Twenty-two patients underwent surgery; one patient arrived at the emergency room with unstable clinical conditions and died before being treated. Fourteen cases (60.9%) were located at the infrarenal aorta, while three cases (13.0%) were pararenal aortic aneurysms. Six cases (26.1%) had an iliac arteries localization. Seventeen patients (77.3%) underwent open surgical repair aneurysmectomy with in situ reconstruction, while three cases (13.6%) underwent extra-anatomic revascularization. Three patients (13.6%) underwent the placement of an endoprosthesis, of whom two underwent hybrid procedures, and one EVAR. The latter underwent an early conversion to open repair due to a type I endoleak. The mean length of hospital stay was 35 ± 18.7 days. Five patients (22.7%) died in the immediate postoperative period. In the follow-up of 45.5 ± 41.3 months (range 2-156), we documented six deaths (35.3%), of whom two (11.8%) were aortic-related for a 34.8% overall aortic-related mortality. Eleven patients were alive, with an overall survival of 47.8%.
Mycotic aneurysm is an extremely rare and varied pathology. Open surgical repair showed to be a safe approach because of a complete and aggressive debridement of local infected tissues, with an acceptable long-term mortality rate.
本研究旨在分析我们 30 年来治疗腹主动脉和髂动脉真菌性动脉瘤的早期和晚期结果。
本回顾性队列研究通过分析意大利罗马 Fondazione Policlinico Universitario Gemelli-IRCCS 血管外科单元在 1989 年 9 月至 2019 年 10 月期间收集的前瞻性数据,比较了所有真菌性动脉瘤患者的结果。
纳入 23 例真菌性动脉瘤患者。22 例患者接受了手术治疗;1 例患者因不稳定的临床状况到达急诊室,并在治疗前死亡。14 例(60.9%)位于肾下主动脉,3 例(13.0%)为肾周主动脉瘤。6 例(26.1%)位于髂动脉。17 例(77.3%)行开放手术动脉瘤切除术原位重建,3 例(13.6%)行非解剖重建。3 例(13.6%)行血管内支架植入术,其中 2 例为杂交手术,1 例为 EVAR。后者因 1 型内漏而行早期转为开放修复。平均住院时间为 35 ± 18.7 天。5 例(22.7%)在术后即刻死亡。在 45.5 ± 41.3 个月(2-156 个月)的随访中,我们记录了 6 例死亡(35.3%),其中 2 例(11.8%)与主动脉相关,总的主动脉相关死亡率为 34.8%。11 例患者存活,总体生存率为 47.8%。
真菌性动脉瘤是一种极其罕见且多样的疾病。开放手术修复显示是一种安全的方法,因为可以彻底清除局部感染组织,并具有可接受的长期死亡率。