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胸主动脉和腹主动脉及髂动脉瘤真菌性动脉瘤的手术治疗策略:长期随访数据分析。

Surgical strategy for treating mycotic aneurysms of thoracic and abdominal aorta and iliac artery: Analysis of long-term follow-up data.

机构信息

Department of Cardiovascular Surgery, 13863Hyogo Prefectural Amagasaki General Medical Center, Hyogo, Japan.

出版信息

Asian Cardiovasc Thorac Ann. 2022 Oct;30(8):906-911. doi: 10.1177/02184923221119916. Epub 2022 Aug 9.

Abstract

Mycotic aneurysms of the aorta and iliac arteries are rare, but life-threatening conditions. We reviewed our experience to determine the best surgical strategy. Between 2007 and 2015, we operated 14 patients with mycotic aneurysms of the aortic arch (  =  6), descending aorta (  =  1), thoracoabdominal aorta (  =  2), abdominal aorta (  =  4), and iliac artery (  =  1). The mean age was 70.4  ±  8.8 years, and 10 males were included. Blood culture, tissue culture, or both were positive in 11 patients. Four of five patients with mycotic aneurysms of the abdominal aorta and iliac artery underwent extra-anatomical bypass. Ten underwent in-situ graft replacement for managing mycotic aneurysms of the thoracic aorta. One patient with a mycotic thoracoabdominal aortic aneurysm underwent visceral bypass of the descending aorta and extra-anatomical bypass. Omental pedicle grafting was performed in 10 patients. The mean follow-up period was 8.6  ±  3.1 years. Three patients (21.4%) died. Recurrent infection was observed in one patient with a mycotic aneurysm of iliac artery three months after the initial surgery. The patient underwent extra-anatomical bypass with omental pedicle grafting as a redo. Nine patients were discharged, and no recurrence of infection was observed. Two patients died of cancer and heart failure. The five- and seven-year survival rates were 100% ± 0.0% and 85.7% ± 13.2%, respectively. A combination of radical debridement of the infectious source and omental pedicle grafting with either in-situ graft replacement or extra-anatomical bypass is an effective strategy.

摘要

主动脉和髂动脉的真菌性动脉瘤较为罕见,但危及生命。我们回顾了我们的经验,以确定最佳的手术策略。在 2007 年至 2015 年期间,我们对 14 例主动脉弓(  =  6)、降主动脉(  =  1)、胸腹主动脉(  =  2)、腹主动脉(  =  4)和髂动脉(  =  1)的真菌性动脉瘤患者进行了手术。平均年龄为 70.4  ±  8.8 岁,包括 10 名男性。11 例患者的血培养、组织培养或两者均为阳性。4 例腹主动脉和髂动脉真菌性动脉瘤患者行外解剖旁路。10 例胸主动脉真菌性动脉瘤行原位移植物置换。1 例胸腹主动脉真菌性动脉瘤患者行降主动脉内脏旁路和外解剖旁路。10 例患者行网膜蒂移植。平均随访时间为 8.6  ±  3.1 年。3 例患者(21.4%)死亡。1 例髂动脉真菌性动脉瘤患者术后 3 个月再次出现感染。患者行外解剖旁路加网膜蒂移植。9 例患者出院,未再发生感染。2 例患者死于癌症和心力衰竭。5 年和 7 年生存率分别为 100% ± 0.0%和 85.7% ± 13.2%。彻底清除感染源,联合网膜蒂移植,原位移植物置换或外解剖旁路是一种有效的策略。

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