Borg E, Spens K E, Tonnquist I
Department of Audiology, Karolinska Hospital, Stockholm, Sweden.
Scand Audiol Suppl. 1988;30:161-4.
Brain maps of late auditory evoked cortical potentials were obtained with the Brain Atlas III system in school-aged children and adults. All subjects were judged as neurologically normal, right-handed, and having normal hearing. The stimulus was a 100 ms burst of 500 Hz pure tone at 75 dB HL presented separately to the left and right ear. The results showed a frontoparietal maximum of negative activity corresponding to N1 and designated as the focus of N1 (FN1). FN1 had latencies of 108 ms (left stimulation (stim] and 113 ms (right stim) and amplitudes of -6.0 microV (left stim) and -4.8 microV (right stim) in children and a latency of 90 ms and an amplitude of -6.5 microV in adults. Among the children, more had ipsilateral than contralateral FN1, usually on the right side. The distance between the centers of gravity of FN1s obtained on stimulation of the two ears was significantly smaller in the maps of children than adults (p less than 0.01). The present findings indicated that the topography of the electrical activity changes during adolescence.
使用Brain Atlas III系统获取了学龄儿童和成人晚期听觉诱发皮层电位的脑图谱。所有受试者经判断神经功能正常、惯用右手且听力正常。刺激为在75 dB HL下分别向左耳和右耳呈现的500 Hz纯音的100 ms脉冲串。结果显示，对应于N1的负性活动在额顶叶出现最大值，并被指定为N1的焦点（FN1）。儿童中，FN1的潜伏期在左耳刺激时为108 ms，右耳刺激时为113 ms，振幅在左耳刺激时为 -6.0 μV，右耳刺激时为 -4.8 μV；成人中，FN1的潜伏期为90 ms，振幅为 -6.5 μV。在儿童中，同侧FN1比 contralateral FN1更多，通常在右侧。在双耳刺激时获得的FN1重心之间的距离在儿童图谱中比成人图谱中显著更小（p小于0.01）。目前的研究结果表明，电活动的地形图在青春期会发生变化。
