丹麦城市地区（腓特烈斯贝）1959 - 1985年尸检中胆结石的患病率。

The prevalence of gallstones in autopsies from a Danish urban area. Frederiksberg, 1959-1985.

作者信息

Teilum D, Olsen B

机构信息

Dept. of Surgery K, Frederiksberg Hospital, Denmark.

出版信息

Scand J Gastroenterol. 1988 Sep;23(7):813-6. doi: 10.3109/00365528809090765.

DOI:10.3109/00365528809090765

PMID:3227296

Abstract

The prevalence of gallstones and cholecystectomies (S + R) was reviewed in nine annual autopsy series, from 1959 to 1985. The investigation confirmed the expectancy of more S + R with increasing age and among women. The median sex ratio was 1.6 (range, 1.3-1.7). It is noteworthy, however, that although the number of elderly people in the autopsy material increased during the period, there was a significant decrease in the prevalence of S + R (p = 2 X 10(-8]. The total prevalence for men decreased from 26% to 18% (p = 2 X 10(-3] and for women from 44% to 31% (p less than 10(-10]. The most striking decrease was seen in the age groups from 60 to 80 years. After a possible culmination during the period from 1920 to 1960, the number of gallstones seemed to level off again. The rates were the same as at present in other Danish investigations from the Copenhagen area (1889, 1911, and 1920-21).

摘要

对1959年至1985年九个年度尸检系列中胆结石和胆囊切除术（S+R）的患病率进行了回顾。调查证实，随着年龄增长以及在女性中，S+R的预期发生率更高。中位性别比为1.6（范围为1.3 - 1.7）。然而，值得注意的是，尽管在此期间尸检材料中的老年人数量有所增加，但S+R的患病率却显著下降（p = 2×10⁻⁸）。男性的总患病率从26%降至18%（p = 2×10⁻³），女性从44%降至31%（p＜10⁻¹⁰）。最显著的下降出现在60至80岁年龄组。在1920年至1960年期间可能达到顶峰之后，胆结石的数量似乎再次趋于平稳。这些比率与哥本哈根地区其他丹麦调查（1889年、1911年以及1920 - 21年）目前的比率相同。