Vriend W H, Hoffman S L, Silaban T, Zaini M
Regency (Kabupaten) Hospital and Health Service, Irian Jaya, Indonesia.
Trop Geogr Med. 1988 Oct;40(4):298-303.
Between 1978 and 1982, 14 patients underwent splenectomy for disabling massive splenomegaly at the Regency Hospital in Wamena in the highlands of Irian Jaya, Indonesia. All patients were clinically diagnosed as having tropical splenomegaly syndrome (hyperreactive malarial splenomegaly), but in no case was the diagnosis confirmed. In May 1984 nurses and physicians caring for these 14 patients were asked to fill in a questionnaire regarding the patients' conditions. Two to 6 years after splenectomy, 8 of the 14 patients were alive and able to work; at least 6 of the 8 at normal or near normal capacity. One patient died 4 days after surgery and 5 died from 2 to 20 months after surgery. We conclude that splenectomy is beneficial for some highly selected patients with the clinical diagnosis of tropical splenomegaly syndrome.
1978年至1982年间，印度尼西亚伊里安查亚高地瓦梅纳摄政医院有14例患者因严重脾肿大导致功能障碍而接受了脾切除术。所有患者临床诊断为热带脾肿大综合征（高反应性疟疾脾肿大），但无一例诊断得到证实。1984年5月，要求护理这14例患者的护士和医生填写一份关于患者病情的问卷。脾切除术后2至6年，14例患者中有8例存活且能够工作；这8例中至少6例能力正常或接近正常。1例患者术后4天死亡，5例在术后2至20个月死亡。我们得出结论，脾切除术对一些临床诊断为热带脾肿大综合征的经过严格挑选的患者有益。
