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Tocilizumab in patients with symptomatic Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.托珠单抗治疗有症状的卡波西肉瘤疱疹病毒相关多中心性Castleman病患者。
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High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy.高剂量齐多夫定联合缬更昔洛韦治疗卡波西肉瘤疱疹病毒相关多中心 Castleman 病：病毒激活细胞毒性治疗的初步研究。
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Coexistence of disseminated Kaposi sarcoma and multicentric Castleman disease in an HIV-infected patient under viral suppression.HIV 感染者病毒抑制状态下弥漫性卡波西肉瘤和多中心 Castleman 病共存。
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Rituximab as retreatment for rituximab pretreated HIV-associated multicentric Castleman disease.利妥昔单抗用于经利妥昔单抗预处理的HIV相关多中心Castleman病的再次治疗。
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Rituximab plus liposomal doxorubicin in HIV-infected patients with KSHV-associated multicentric Castleman disease.利妥昔单抗联合脂质体阿霉素治疗合并卡波西肉瘤相关多中心Castleman病的HIV感染患者。
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Recent advances in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.卡波西肉瘤疱疹病毒相关多中心 Castleman 病的最新进展。
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Lymphoproliferations in People Living with HIV: Oncogenic Pathways, Diagnostic Challenges, and New Therapeutic Opportunities.HIV感染者的淋巴细胞增殖：致癌途径、诊断挑战及新的治疗机遇
Cancers (Basel). 2025 Jun 22;17(13):2088. doi: 10.3390/cancers17132088.
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HIV-associated cancers and lymphoproliferative disorders caused by Kaposi sarcoma herpesvirus and Epstein-Barr virus.人类免疫缺陷病毒相关癌症和卡波西肉瘤疱疹病毒与 Epstein-Barr 病毒引起的淋巴组织增生性疾病。
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Pacritinib inhibits proliferation of primary effusion lymphoma cells and production of viral interleukin-6 induced cytokines.帕西替尼抑制原发性渗出性淋巴瘤细胞的增殖以及病毒白细胞介素-6诱导的细胞因子的产生。
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Pediatric HIV+ Kaposi sarcoma exhibits clinical, virological, and molecular features different from the adult disease.儿科 HIV+ 卡波西肉瘤表现出与成人疾病不同的临床、病毒学和分子特征。
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本文引用的文献

1
Emergence of Kaposi's Sarcoma Herpesvirus-Associated Complications Following Corticosteroid Use in TB-IRIS.结核病免疫重建炎症综合征中使用皮质类固醇后卡波西肉瘤疱疹病毒相关并发症的出现
Open Forum Infect Dis. 2018 Oct 12;5(10):ofy217. doi: 10.1093/ofid/ofy217. eCollection 2018 Oct.
2
HIV-Associated Cancers and Related Diseases.艾滋病相关癌症及相关疾病
N Engl J Med. 2018 Mar 15;378(11):1029-1041. doi: 10.1056/NEJMra1615896.
3
Treatment of Kaposi Sarcoma Herpesvirus-Associated Multicentric Castleman Disease.卡波西肉瘤疱疹病毒相关多中心性Castleman病的治疗
Hematol Oncol Clin North Am. 2018 Feb;32(1):75-88. doi: 10.1016/j.hoc.2017.09.007.
4
Relapse of HHV8-positive multicentric Castleman disease following rituximab-based therapy in HIV-positive patients.利妥昔单抗治疗 HIV 阳性患者后，HHV8 阳性多中心 Castleman 病复发。
Blood. 2017 Apr 13;129(15):2143-2147. doi: 10.1182/blood-2016-10-747477. Epub 2017 Jan 31.
5
Rituximab plus liposomal doxorubicin in HIV-infected patients with KSHV-associated multicentric Castleman disease.利妥昔单抗联合脂质体阿霉素治疗合并卡波西肉瘤相关多中心Castleman病的HIV感染患者。
Blood. 2014 Dec 4;124(24):3544-52. doi: 10.1182/blood-2014-07-586800. Epub 2014 Oct 20.
6
Human and viral interleukin-6 and other cytokines in Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.人类和病毒白细胞介素-6 和其他细胞因子在卡波西肉瘤疱疹病毒相关的多中心 Castleman 病中的作用。
Blood. 2013 Dec 19;122(26):4189-98. doi: 10.1182/blood-2013-08-519959. Epub 2013 Oct 30.
7
HHV-8-encoded viral IL-6 collaborates with mouse IL-6 in the development of multicentric Castleman disease in mice.HHV-8 编码的病毒 IL-6 与小鼠 IL-6 合作在小鼠中引发多中心 Castleman 病。
Blood. 2012 May 31;119(22):5173-81. doi: 10.1182/blood-2011-09-377705. Epub 2012 Apr 9.
8
High-dose zidovudine plus valganciclovir for Kaposi sarcoma herpesvirus-associated multicentric Castleman disease: a pilot study of virus-activated cytotoxic therapy.高剂量齐多夫定联合缬更昔洛韦治疗卡波西肉瘤疱疹病毒相关多中心 Castleman 病：病毒激活细胞毒性治疗的初步研究。
Blood. 2011 Jun 30;117(26):6977-86. doi: 10.1182/blood-2010-11-317610. Epub 2011 Apr 12.
9
How I treat HIV-associated multicentric Castleman disease.我如何治疗 HIV 相关多中心 Castleman 病。
Blood. 2010 Nov 25;116(22):4415-21. doi: 10.1182/blood-2010-07-290213. Epub 2010 Aug 5.
10
Influence of humanized anti-IL-6R antibody, tocilizumab on the activity of soluble gp130, natural inhibitor of IL-6 signaling.人源化抗IL-6R抗体托珠单抗对IL-6信号天然抑制剂可溶性gp130活性的影响。
Rheumatol Int. 2009 Feb;29(4):397-401. doi: 10.1007/s00296-008-0703-8. Epub 2008 Sep 20.

Tocilizumab in patients with symptomatic Kaposi sarcoma herpesvirus-associated multicentric Castleman disease.

作者信息

Ramaswami Ramya, Lurain Kathryn, Peer Cody J, Serquiña Anna, Wang Victoria, Widell Anaida, Goncalves Priscila, Steinberg Seth M, Marshall Vickie, George Jomy, Figg William D, Whitby Denise, Ziegelbauer Joseph, Uldrick Thomas S, Yarchoan Robert

机构信息

HIV & AIDS Malignancy Branch.

Clinical Pharmacology Program, and.

出版信息

Blood. 2020 Jun 18;135(25):2316-2319. doi: 10.1182/blood.2019004602.

DOI:10.1182/blood.2019004602
PMID:32276276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7316216/
Abstract
摘要