Hydroxycinnamoyl Amino Acids Conjugates: A Chiral Pool to Distinguish Commercially Exploited spp.

The synthesis of five hydroxycinnamoyl amides (HCAs) was accomplished and their identification and quantification in the green coffee bean samples of , , and was performed. The HCAs -coumaroyl--tyrosine , caffeoyl--phenylalanine , caffeoyl--tyrosine , and -coumaroyl--tryptophan were characteristic of the species while caffeoyl--tryptophan was present in both and , but with higher content in . The HCAs presence was also analyzed in for the first time and none of the targeted compounds was found, indicating that this species is very similar to species. Between samples from various origins, significant differences were observed regarding the presence of all the HCAs, with from Tanzania containing all five derivatives.