Gurevich O A, Chertkov I L
Biull Eksp Biol Med. 1977 Mar;83(3):339-42.
A focusl of hemopoiesis appearing after the transplantation of a bone marrow fragment of C57BL mice to syngeneic mice (under the kidney capsule) contained more hemopoietic cells than in transplantation to the semisyngeneic (CBA X C57BL) FI recipient. Experiments were conducted with a secondary seeding by intravenous injection of hemopoietic cells of the C57BL transplant genotype into the transplant depopulated by irradiation; it was shown that these differences were caused by lesser dimensions of the hemopoietic microenvironment in the focus in the hybrid organism in comparison with such in the syngeneic system. Thus, the hybrid resistance was expressed not only to the hemopoietic cells, but also to the stromal precursors transferring the hemopoietic microenvironment.
将C57BL小鼠的骨髓片段移植到同基因小鼠（肾包膜下）后出现的造血灶比移植到半同基因（CBA×C57BL）F1受体小鼠中含有更多的造血细胞。通过静脉注射C57BL移植基因型的造血细胞对经照射而细胞耗竭的移植灶进行二次接种，开展了相关实验；结果表明，与同基因系统相比，杂种生物体中造血灶内造血微环境的尺寸较小，从而导致了这些差异。因此，杂种抗性不仅表现在对造血细胞上，还表现在对传递造血微环境的基质前体上。
