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机器人手术后的再入院和并发症:综合癌症中心 10000 例手术的经验。

Readmission and complications after robotic surgery: experience of 10,000 operations at a comprehensive cancer center.

机构信息

Department of Surgery, City of Hope National Medical Center, 1500 E. Duarte Rd, MOB L002H, Duarte, CA, 91010, USA.

Department of Biostatistics, City of Hope National Medical Center, Duarte, CA, USA.

出版信息

J Robot Surg. 2021 Feb;15(1):37-44. doi: 10.1007/s11701-020-01077-4. Epub 2020 Apr 10.

Abstract

Evaluation of safety is of paramount importance with adoption of novel surgical technology. Although robotic surgery has become widely used in oncologic surgery, analysis of safety is lacking in comparison to traditional techniques. Standardized assessment of robotic surgical outcomes and adverse events following oncologic surgery is necessary for quality improvement with innovative technology. Between 2003 and 2016, 10,013 unique robotic operations were performed in 9,858 patients. Our prospectively maintained database was retrospectively reviewed for hospital readmissions and Clavien-Dindo grade ≥ 2 complications within 30 days. Multivariable logistic regression was used to identify predictors of surgical complications and hospital readmissions. Cases were stratified by discipline: genitourinary (n = 8240), gynecologic (n = 857), thoracic (n = 457), gastrointestinal (n = 322), hepatobiliary (n = 60), ear/nose/throat (n = 44) and general (n = 33). Intraoperative complications occurred in 42 surgeries (0.4%). Postoperative complications occurred in 946 patients [9.4%, highest grade 2 (n = 574), 3 (n = 288), 4 (n = 72), 5 (n = 10)]. Most frequent complications were ileus (154, 16.3%), anemia (91, 9.6%), cardiac arrhythmia (62, 6.6%), deep vein thrombosis/pulmonary embolus (47, 5.0%), wound infection (45, 4.8%) and urinary leak (43, 4.5%). 405 patients (4.0%) required readmission. Most common causes for hospital readmission were ileus (44, 10.9%), urinary leak (23, 5.7%), urinary tract infection (23, 5.7%), intra-abdominal abscess/fluid collection (23, 5.7%), and small bowel obstruction (19, 4.7%). On multivariable analysis, longer operative time and older age predicted complications and readmissions (p ≤ 0.02). Robotic-assisted surgery appears a safe for oncologic surgery with acceptable hospital readmission and complication rates. Older age and longer operative time were associated with complications and readmission.

摘要

评估安全性对于采用新型手术技术至关重要。尽管机器人手术已广泛应用于肿瘤外科,但与传统技术相比,其安全性分析仍存在不足。为了提高创新技术的质量,有必要对机器人手术的结果和肿瘤手术后的不良事件进行标准化评估。2003 年至 2016 年,在 9858 名患者中进行了 10013 例独特的机器人手术。我们前瞻性维护的数据库对 30 天内的医院再入院和 Clavien-Dindo 分级≥2 并发症进行了回顾性分析。多变量逻辑回归用于确定手术并发症和医院再入院的预测因素。病例按学科分层:泌尿生殖系统(n=8240)、妇科(n=857)、胸科(n=457)、胃肠科(n=322)、肝胆科(n=60)、耳鼻喉科(n=44)和普外科(n=33)。术中并发症发生在 42 例手术中(0.4%)。946 例患者发生术后并发症[9.4%,最高 2 级(n=574)、3 级(n=288)、4 级(n=72)、5 级(n=10)]。最常见的并发症是肠梗阻(154 例,16.3%)、贫血(91 例,9.6%)、心律失常(62 例,6.6%)、深静脉血栓形成/肺栓塞(47 例,5.0%)、伤口感染(45 例,4.8%)和尿漏(43 例,4.5%)。405 例患者(4.0%)需要再次入院。医院再入院的最常见原因是肠梗阻(44 例,10.9%)、尿漏(23 例,5.7%)、尿路感染(23 例,5.7%)、腹腔脓肿/积液(23 例,5.7%)和小肠梗阻(19 例,4.7%)。多变量分析显示,手术时间延长和年龄较大与并发症和再入院相关(p≤0.02)。机器人辅助手术在肿瘤外科中是安全的,其医院再入院和并发症发生率可接受。年龄较大和手术时间较长与并发症和再入院相关。

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