Department of Plant and Environmental Sciences, School of Health Research, Clemson University Pee Dee Research and Education Centre, Florence, SC, USA.
Carlsberg Research Laboratory, Copenhagen, Denmark.
Methods Mol Biol. 2020;2124:3-18. doi: 10.1007/978-1-0716-0356-7_1.
The present and subsequent chapters in this volume are dedicated to the life and research of Professor Diter von Wettstein who contributed immensely to the development of science and education. His contributions spanned various fields of science such as genetics, physiology, ultrastructural analysis, molecular biology, genomics, and biotechnology including genome editing. He performed and promoted pioneering research in the fields of epigenetics, directed evolution of enzymes, synthetic biology (promoter and gene optimizations), and genomics (genome sequencing of baker's yeast). Glimpses of his time at the Carlsberg Laboratory and Washington State University, with examples from the research performed at these institutions, are included in this chapter. His life is an inspiration to the next generation of biologists. Despite difficult situations, his persistent efforts and keen desire to learn enabled him to overcome obstacles. He always tried to attain the best, excelling in translating fundamental knowledge into applications.
本卷的当前和后续章节致力于纪念迪特·冯·维特斯坦教授的生平和研究，他为科学和教育的发展做出了巨大贡献。他的贡献涵盖了遗传学、生理学、超微结构分析、分子生物学、基因组学和生物技术（包括基因组编辑）等多个科学领域。他在表观遗传学、酶的定向进化、合成生物学（启动子和基因优化）和基因组学（面包酵母基因组测序）等领域开展并推动了开创性的研究。本章收录了他在嘉士伯实验室和华盛顿州立大学的时光片段，以及在这些机构进行的研究示例。他的一生激励着下一代生物学家。尽管面临困难，他始终坚持不懈地努力学习，克服了重重障碍。他总是力求做到最好，将基础知识出色地转化为应用。
