酒精性肝病的门诊管理。
Outpatient management of alcohol-related liver disease.
机构信息
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science Rochester, MN, USA.
Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine and Science Rochester, MN, USA.
出版信息
Lancet Gastroenterol Hepatol. 2020 May;5(5):485-493. doi: 10.1016/S2468-1253(19)30415-7.
Abstract
Alcohol-related liver disease has become the leading indication for liver transplantation in the USA, partly due to an increase in the prevalence of high-risk drinking behaviour and alcohol use disorder, particularly among young women. Achieving sustained alcohol abstinence might not only prevent the development and progression of alcohol-related liver disease, but could also lead to clinically significant improvements, even in the advanced stages of disease. In this Series paper, we discuss the diagnosis and outpatient management of alcohol-related liver disease, with an emphasis on treatment options for alcohol use disorder and the assessment of nutritional status.
摘要
酒精相关肝病已成为美国肝移植的主要适应证，部分原因是高危饮酒行为和酒精使用障碍（尤其是在年轻女性中）的流行率增加。实现持续的酒精禁欲不仅可以预防酒精相关肝病的发生和进展，而且即使在疾病的晚期也可能导致临床显著改善。在本系列论文中，我们讨论了酒精相关肝病的诊断和门诊管理，重点介绍了酒精使用障碍的治疗选择和营养状况评估。
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Systematic review with meta-analysis: high mortality in patients with non-severe alcoholic hepatitis.系统评价与荟萃分析：非重症酒精性肝炎患者死亡率高。
Aliment Pharmacol Ther. 2019 Aug;50(3):249-257. doi: 10.1111/apt.15376. Epub 2019 Jun 23.
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