酒精相关肝病患者的酒精使用障碍治疗：创新方法和行动呼吁。
Treatment of alcohol use disorder in patients with alcohol-associated liver disease: Innovative approaches and a call to action.
机构信息
Department of Medicine, Digestive Diseases, & Program in Addiction Medicine, Yale School of Medicine, New Haven, Connecticut, USA.
Department of Internal Medicine, Addiction Unit, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, 08916, Badalona (Barcelona), Spain.
出版信息
Addict Sci Clin Pract. 2024 Mar 19;19(1):19. doi: 10.1186/s13722-024-00448-8.
Alcohol-associated liver disease is currently the leading cause of liver transplantation and liver deaths both in Europe and the United States. Efficacious treatments exist for alcohol use disorder, but they are seldomly prescribed for patients who need them. Besides, the presence of liver cirrhosis can complicate pharmacological treatment choices. In this review, we discuss established and innovative treatment strategies to treat unhealthy alcohol use in patients with alcohol-associated liver disease. We also describe the experience of our own institutions, Hospital Universitari Germans Trias i Pujol in Badalona (Spain) and Yale-New Haven Health and Yale Medicine (Connecticut. United States of America).
酒精相关性肝病目前是欧洲和美国肝移植和肝死亡的主要原因。对于酒精使用障碍，存在有效的治疗方法，但很少为需要的患者开这些药物。此外，肝硬化的存在会使药物治疗的选择变得复杂。在这篇综述中，我们讨论了用于治疗酒精相关性肝病患者不健康饮酒的既定和创新治疗策略。我们还描述了我们自己的机构的经验，西班牙巴达洛纳的 Germans Trias i Pujol 大学医院和美国康涅狄格州耶鲁-纽黑文健康和耶鲁大学医学。
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