Myllylä V V, Sotaniemi K A, Pyhtinen J
Department of Neurology, University of Oulu, Finland.
Acta Neurol Scand. 1988 Sep;78(3):228-33. doi: 10.1111/j.1600-0404.1988.tb03651.x.
The significance of cerebral CT in neurological diagnostic practice was analysed in this prospective study on 1191 consecutive patients investigated during a one-year period. CT abnormalities were detected in 601 cases (51%), local hemispheral lesions (22%) generalized atrophy (19%) and infratentorial lesions (5%) being the most common findings. In the cases which had presented at referral to CT with clinical indices suggesting cerebral pathology the CT was abnormal in 71% (379 of 537) while the percentage was 34 (222 of 654) in the cases in which CT was performed for exclusion criteria. The clinical diagnostic reviewed by CT accuracy was 88% in cerebral tumours, 69% in cerebral infarction and from 83% to 94% in various intracranial hemorrhages but only 51% in cerebral atrophy which was the most common CT finding without clinical correlates. Apart from atrophy, CT revealed other pathology than clinically suggested in 147 cases (e.g. cerebral infarct in 58, hemorrhage in 16, tumour in 8 and diverse abnormalities in 54 cases). Contrast medium enhancement (used in 45% of the scans) provided more information when compared with the plain scan in 16% (86 of 537), no more than 3 lesions (0.6% of the enhanced scans; 2 meningeomas and one vascular malformation) being visible with enhancement only.
在这项前瞻性研究中,对连续1191例在一年期间接受检查的患者进行分析,以探讨脑部CT在神经诊断实践中的意义。601例(51%)检测到CT异常,最常见的发现是局部半球病变(22%)、广泛性萎缩(19%)和幕下病变(5%)。在转诊进行CT检查时临床指标提示有脑部病变的病例中,CT异常的占71%(537例中的379例),而因排除标准进行CT检查的病例中这一比例为34%(654例中的222例)。经CT准确性评估的临床诊断准确率在脑肿瘤中为88%,在脑梗死中为69%,在各种颅内出血中为83%至94%,但在脑萎缩中仅为51%,脑萎缩是最常见的CT表现且无临床相关症状。除萎缩外,CT在147例中显示出比临床提示更多的病变(例如,脑梗死58例、出血16例、肿瘤8例以及54例有多种异常)。增强扫描(45%的扫描使用)与平扫相比,在16%(537例中的86例)的病例中提供了更多信息,仅增强扫描可见不超过3个病变(增强扫描的0.6%;2例脑膜瘤和1例血管畸形)。