Department of Otolaryngology-Head and Neck Surgery, University of Missouri-Columbia, One Hospital Drive, Suite MA314, Columbia, MO 65212, USA.
Immunol Allergy Clin North Am. 2020 May;40(2):295-302. doi: 10.1016/j.iac.2019.12.006. Epub 2020 Jan 8.
Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heteromorphic disease with both medical and surgical aspects to its treatment. CRSwNP is a chronic inflammatory condition with exacerbations that can be controlled through surgical and/or medical interventions, including biological agents. The role of biological agents in the treatment of CRSwNP as well as the patient characteristics that make suitable candidates for biologics are discussed.
伴有鼻息肉的慢性鼻-鼻窦炎(CRSwNP)是一种具有多种形态的疾病,其治疗兼具医疗和手术方面。CRSwNP 是一种慢性炎症性疾病,可通过手术和/或包括生物制剂在内的医疗干预来控制其加重。本文讨论了生物制剂在 CRSwNP 治疗中的作用,以及适合使用生物制剂的患者特征。