Benzakoun J, Robert C, Legrand L, Pallud J, Meder J-F, Oppenheim C, Dhermain F, Edjlali M
Radiology Department, GHU de Paris, centre hospitalier Sainte-Anne, 1, rue Cabanis, 75014 Paris, France; Université de Paris, 85, boulevard Saint-Germain, 75006 Paris, France; Imabrain, Institut de psychiatrie et neurosciences de Paris (IPNP), 102-108, rue de la Santé, 75014 Paris, France; Inserm, U1266, 102, rue de la Santé, 75013 Paris, France.
Medical Physics Department, Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif, France; Molecular Radiotherapy, Gustave-Roussy, 114, rue Édouard-Vaillant, 94805 Villejuif, France; Inserm, 114, rue Édouard-Vaillant, 94805 Villejuif, France; Paris-Sud University, Paris-Saclay University, 114, rue Édouard-Vaillant, 94805 Villejuif, France.
Cancer Radiother. 2020 Aug;24(5):453-462. doi: 10.1016/j.canrad.2020.03.005. Epub 2020 Apr 8.
Neuroimaging and especially MRI has emerged as a necessary imaging modality to detect, measure, characterize and monitor brain tumours. Advanced MRI sequences such as perfusion MRI, diffusion MRI and spectroscopy as well as new post-processing techniques such as automatic segmentation of tumours and radiomics play a crucial role in characterization and follow up of brain tumours. The purpose of this review is to provide an overview on anatomical and functional MRI use for brain tumours boundaries determination and tumour characterization in the specific context of radiotherapy. The usefulness of anatomical and functional MRI on particular challenges posed by radiotherapy such as pseudo progression and pseudo esponse and new treatment strategies such as dose painting is also described.
神经影像学，尤其是磁共振成像（MRI），已成为检测、测量、表征和监测脑肿瘤必不可少的成像方式。先进的MRI序列，如灌注MRI、扩散MRI和波谱分析，以及新的后处理技术，如肿瘤自动分割和放射组学，在脑肿瘤的表征和随访中发挥着关键作用。本综述的目的是概述在放射治疗的特定背景下，解剖学和功能MRI在确定脑肿瘤边界和肿瘤表征方面的应用。还描述了解剖学和功能MRI在应对放射治疗带来的特殊挑战（如假性进展和假性反应）以及新的治疗策略（如剂量描绘）方面的有用性。
