完全性胼胝体切开术与前胼胝体切开术患者的癫痫发作结局：结局分析
Seizure Outcomes in Patients with Complete versus Anterior Corpus Callosotomy: Analysis of Outcome.
作者信息
Thohar Arifin Muhamad, Muttaqin Zainal, Bakhtiar Yuriz, Andar Erie, Priambada Dody, Kurnia Happy, Risdianto Ajid, Tsaniadi Krisna, Kusnarto Gunadi, Bunyamin Jacob
机构信息
Department of Neurosurgery, Faculty of Medicine, Diponegoro University, Kariadi Hospital, Semarang, Indonesia.
出版信息
Int J Gen Med. 2020 Mar 31;13:105-110. doi: 10.2147/IJGM.S247438. eCollection 2020.
INTRODUCTION
Corpus callosotomy (CCT) is a palliative procedure to treat injurious drop attacks or multifocal/generalized seizures in which resection of the epileptogenic focus is not feasible. We are presenting our experience in treating intractable epilepsy patients by CCT procedures.
METHODS
We observed 16 patients who underwent callosotomy (male to female ratio 7:9; adult to pediatric ratio 3:13). Initial seizure frequency was reported ranged from 1 to 2 attacks daily to very often (more than 20 episodes daily).
RESULTS
Our observation showed that among patients with drop attacks, complete and >90% seizure freedom was reported by 4 and 6 of 13 patients, respectively (76.9% combined).
CONCLUSION
Our observation showed that corpus callosotomy yielded good outcome in patients with intractable epilepsy in Indonesia. Our observation showed total callosotomy achieved complete seizure freedom better compared to partial callosotomy patients.
引言
胼胝体切开术（CCT）是一种姑息性手术，用于治疗无法进行致痫灶切除的损伤性跌倒发作或多灶性/全身性癫痫。我们在此介绍我们通过CCT手术治疗难治性癫痫患者的经验。
方法
我们观察了16例行胼胝体切开术的患者（男女比例为7:9；成人与儿童比例为3:13）。据报告，初始癫痫发作频率从每天1至2次发作到非常频繁（每天超过20次发作）不等。
结果
我们的观察表明，在跌倒发作患者中，13例患者分别有4例和6例报告完全无发作且发作自由度>90%（合计76.9%）。
结论
我们的观察表明，胼胝体切开术在印度尼西亚难治性癫痫患者中取得了良好的效果。我们的观察表明，与部分胼胝体切开术患者相比，完全胼胝体切开术实现完全无发作的效果更好。
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