Sequeira Sean Bertram, Scott James, Novicoff Wendy, Cui Quanjun
Department of Orthopedic Surgery, University of Virginia School of Medicine, Charlottesville, VA 22908, United States.
World J Orthop. 2020 Mar 18;11(3):184-196. doi: 10.5312/wjo.v11.i3.184.
Total knee arthroplasty is one of the most successful operations performed worldwide today. Patellar clunk syndrome (PCS) is a postoperative complication that arises due to the development of a fibrous nodule along the undersurface of the quadriceps tendon. The current literature on PCS has not yet come to a consensus regarding its etiology. To date, this is the first study that analyzes the existing literature on PCS in order to generate a conclusion regarding its etiology. It is hypothesized that prosthesis design is the main component behind the development of PCS.
To determine the etiology of PCS and its association with pre and post-operative characteristics of the prosthesis and native knee.
We conducted a systematic review according to the PRISMA guidelines by searching through PubMed, Cochrane, and Google Scholar from May-July 2018 for cases of PCS using search MeSH terms "patella OR patellar" AND "clunk" OR "catch" OR "crepitus". The search included case series and clinical trials and excluded review articles, yielding 30 articles from the original search and 3 additional articles from reference lists. We extracted data upon the outcomes in patients afflicted with PCS to determine the etiology of PCS. We performed additional bias assessments to validate our search algorithm and results.
Prosthesis design was the metric most frequently implicated in the incidence of PCS, though several other metrics were contributory toward its pathogenesis. Later prosthetic designs incorporate a reduced intercondylar box ratio and box width to reduce contact between the proximal patellar pole and the intercondylar box, thereby reducing incidence of PCS.
The etiology of PCS is multifactorial, owing to the growing metrics that have associations with its incidence. This conclusion is validated by the significance of prosthesis design as the most likely parameter involved in developing PCS since different prosthesis designs are often the result of different parameters. Future studies should be directed at isolating individual prosthetic parameters of prosthesis designs in order to determine what permutation of parameters is most closely associated with the development of PCS.
全膝关节置换术是当今世界上最成功的手术之一。髌咔嗒综合征(PCS)是一种术后并发症,由于股四头肌肌腱下表面出现纤维结节而引发。目前关于PCS的文献尚未就其病因达成共识。迄今为止,这是第一项分析PCS现有文献以得出其病因结论的研究。据推测,假体设计是PCS发生背后的主要因素。
确定PCS的病因及其与假体和天然膝关节术前及术后特征的关联。
我们根据PRISMA指南进行了一项系统评价,于2018年5月至7月通过在PubMed、Cochrane和谷歌学术上搜索,使用医学主题词“髌骨或髌的”以及“咔嗒声”或“卡顿”或“摩擦音”来查找PCS病例。搜索包括病例系列和临床试验,并排除综述文章,最初搜索得到30篇文章,参考文献列表中又有3篇文章。我们提取了PCS患者的相关数据以确定PCS的病因。我们进行了额外的偏倚评估以验证我们的搜索算法和结果。
假体设计是PCS发生率最常涉及的指标,不过其他几个指标也对其发病机制有影响。后来的假体设计减小了髁间盒比例和盒宽度,以减少髌骨近端极与髁间盒之间的接触,从而降低了PCS的发生率。
PCS的病因是多因素的,这是由于越来越多的指标与其发生率相关。由于不同的假体设计往往是不同参数的结果,假体设计作为最有可能参与PCS发生的参数的重要性验证了这一结论。未来的研究应致力于分离假体设计的各个假体参数,以确定哪些参数组合与PCS的发生最密切相关。