与长期使用可卡因后急性发作相关的深部毛细血管丛灌注不足。
Hypoperfusion of the deep capillary plexus associated with acute on chronic cocaine use.
作者信息
Carroll William J, Maganti Nenita, Gill Manjot K
机构信息
Department of Ophthalmology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
出版信息
Am J Ophthalmol Case Rep. 2020 Apr 1;18:100684. doi: 10.1016/j.ajoc.2020.100684. eCollection 2020 Jun.
PURPOSE
To illustrate a case of decreased perfusion in the deep capillary plexus seen on ocular coherence tomography angiography in a patient with acute on chronic cocaine use.
OBSERVATIONS
A 69-year-old male who presented with a sudden loss of vision in his right eye following recent use of cocaine. Ocular coherence tomography of the right eye revealed hyperreflectivity within layers of the retina and ocular coherence tomography angiography showed decreased vascular density and flow in the deep capillary plexus.
CONCLUSIONS AND IMPORTANCE
Cocaine use has been associated with systemic and cardiac effects, as well as ocular sequelae. It has been hypothesized to have a role in the pathogenesis of acute macular neuroretinopathy. Here we present the first case of ocular coherence tomography angiography findings of hypoperfusion of the deep capillary plexus in a patient with acute on chronic cocaine use.
目的
阐述1例长期使用可卡因后急性发作患者眼部相干光断层扫描血管造影显示深层毛细血管丛灌注减少的病例。
观察结果
一名69岁男性，近期使用可卡因后右眼突然失明。右眼的眼部相干光断层扫描显示视网膜各层内出现高反射，眼部相干光断层扫描血管造影显示深层毛细血管丛的血管密度和血流减少。
结论及意义
使用可卡因与全身及心脏影响以及眼部后遗症有关。据推测，它在急性黄斑神经视网膜病变的发病机制中起作用。在此，我们报告了首例长期使用可卡因后急性发作患者深层毛细血管丛灌注不足的眼部相干光断层扫描血管造影结果。
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