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中国厦门市(2015 - 2018年)暴露于环境空气污染物对早产的急性影响

Acute Effects of Exposure to Ambient Air Pollutants on Preterm Birth in Xiamen City (2015-2018), China.

作者信息

Huang Sijing, Lin Dianchao, Huang Zhixiong, Yang Lin, Ding Xinyu, Chen Qionghua

机构信息

Department of Obstetrics and Gynecology, The First Affiliated Hospital, School of Medicine, Xiamen University, Xiamen, Fujian 361003, China.

The Key Laboratory of Research and Diagnosis of Gynecological Diseases of Xiamen City, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, China.

出版信息

ACS Omega. 2020 Mar 26;5(13):7462-7467. doi: 10.1021/acsomega.0c00146. eCollection 2020 Apr 7.

Abstract

: Urban energy consumption is one of the important causes of air pollution. The epidemiological risk assessment guided by air pollution is of great significance to the promotion of urban environmental protection. : The work researched the acute impact of exposure to air pollution on preterm birth (PTB) in Xiamen city from 2015 to 2018. Furthermore, the economic losses were assessed as well. : Association of air pollution and PTB with economic losses were assessed using the generalized additive model. : A total of 1991 PTB visits, who are inhabitant in Xiamen, have been investigated. An interquartile range (IQR) (10 μg/m) increase of PM, NO, and SO in the current day corresponded to the increase of 0.64% [95% CI: -1.22, 2.54%], 0.52% [95% CI: -5.21, 6.61%], and 2.33% [95% CI: -6.41, 11.58%] in daily PTB visits. Especially, PTB visits were significantly related with PM and NO in Lag 1 and NO and SO in Lag 2. Furthermore, for multipollutants, an IQR increase in PM, O, and CO, after adjustment with SO, was related with 5.04% [95% CI: -5.90, 17.24], 2.49% [95% CI: -6.07, 11.81], and 7.10% [95% CI: -2.79, 18.00] increase of PTB morbidity, respectively. The estimates of the number of excess PTBs attributed to typical pollutants PM and SO were ∼2400 and 1200 people, respectively, every year. The highest excess PTBs was estimated to occur as a result of PM and SO effects. : Although Xiamen has a relatively low level of air pollution, short-term exposure to NO, SO, and PM was linked to the increase of PTB visits.

摘要

城市能源消耗是空气污染的重要成因之一。以空气污染为导向的流行病学风险评估对推动城市环境保护具有重要意义。该研究探讨了2015年至2018年厦门市空气污染暴露对早产(PTB)的急性影响。此外,还评估了经济损失。使用广义相加模型评估空气污染、PTB与经济损失之间的关联。共调查了1991例居住在厦门的早产病例。当日PM、NO和SO每增加一个四分位数间距(IQR)(10μg/m),每日早产病例分别增加0.64%[95%CI:-1.22,2.54%]、0.52%[95%CI:-5.21,6.61%]和2.33%[95%CI:-6.41,11.58%]。特别是,早产病例与滞后1天的PM和NO以及滞后2天的NO和SO显著相关。此外,对于多种污染物,在对SO进行校正后,PM、O和CO每增加一个IQR,早产发病率分别增加5.04%[95%CI:-5.90,17.24]、2.49%[95%CI:-6.07,11.81]和7.10%[95%CI:-2.79,18.00]。每年归因于典型污染物PM和SO的额外早产病例估计分别约为2400人和1200人。估计由于PM和SO的影响导致的额外早产病例最多。尽管厦门的空气污染水平相对较低,但短期暴露于NO、SO和PM与早产病例的增加有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40e9/7144129/5763a1253fd5/ao0c00146_0001.jpg

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