Department of Neurosurgery, Clinical Neurosciences Center, 175 North Medical Drive East, Salt Lake City, UT, 84132, USA.
Division of Pediatric Neurosurgery, Primary Children's Hospital, University of Utah, Salt Lake City, UT, USA.
Acta Neurochir (Wien). 2020 Jul;162(7):1771-1775. doi: 10.1007/s00701-020-04316-7. Epub 2020 Apr 12.
Brainstem cavernous malformations (CMs) often have high hemorrhage rates and significant posthemorrhage morbidity. The authors present two cases in which magnetic resonance thermography-guided laser interstitial therapy was used for treatment of pontine CMs after recurrent hemorrhage. Both patients showed significant symptomatic improvement and were hemorrhage-free at 12- and 6-month follow-up, respectively. Each had radiographic evidence of lesion involution on serial follow-up imaging. These early results demonstrate this treatment modality may be technically safe; however, larger case numbers and longer follow-up are needed to demonstrate efficacy.
脑干海绵状血管畸形（CM）常伴有较高的出血率和明显的出血后发病率。作者报告了两例桥脑 CM 反复出血后应用磁共振热成像引导激光间质热疗治疗的病例。两名患者的症状均有显著改善，分别在 12 个月和 6 个月的随访中未再出血。连续随访影像学检查均显示病灶退行性变的影像学证据。这些早期结果表明该治疗方法在技术上是安全的；然而，需要更大的病例数量和更长的随访时间来证明其疗效。
