罗伯逊易位杂合性与雄性不育
Robertsonian heterozygosity and male sterility.
作者信息
Gabriel-Robez O, Ratomponirina C, Cranz C, Weill A, Goldschmit P A, Bollack C, Rumpler Y
机构信息
Faculté de Médicine, Institute d'Embryology, Strasbourg/France.
出版信息
Andrologia. 1988 Nov-Dec;20(6):463-6.
PMID:3228212
Abstract
Meiotic and synaptonemal complex studies using electron microscopy were carried out on infertile man with a 13/14 translocation. Synaptonemal complex analysis showed a typical trivalent with incomplete pairing of the acrocentric elements. The sterilizing effect caused by the failure of synapsis is discussed. This pairing failure has a diagnostic value and a poor prognosis.
摘要
对一名患有13/14易位的不育男性进行了使用电子显微镜的减数分裂和联会复合体研究。联会复合体分析显示出一个典型的三价体，近端着丝粒元件配对不完全。讨论了由联会失败导致的绝育效应。这种配对失败具有诊断价值且预后不良。
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