IAKENTRO, Infertility Treatment Center, Thessaloniki, Greece.
Department of Obstetrics and Gynaecology, Medical School, University of Ioannina, Greece.
Eur J Obstet Gynecol Reprod Biol. 2020 May;248:204-210. doi: 10.1016/j.ejogrb.2020.03.042. Epub 2020 Mar 19.
To evaluate surgical outcomes of intracapsular single-layer myomectomy in terms of efficacy and safety as well as examine potential alterations based on kind of surgical approach.
A prospective observational study was performed between January 2010 and December 2018. Women in reproductive age, affected by intramural or subserous myomas (FIGO type 3-6) of 4-14 cm diameter were enrolled. Primary outcomes included initial and final uterine incision length, time to wound healing and uterine rupture in subsequent pregnancies. Furthermore, a sub-analysis was also performed regarding surgical approach, namely laparoscopical or laparoscopically-assisted myomectomy, in order to confirm whether overall observations are similar for both potential surgical approaches.
There were finally 273 patients included in the present study. Overall mean uterine incision was initially 3.1 cm and was shortened to 2.2 cm at the end of operation, indicating a reduction of 29.1 %. Mean estimated blood loss was 154.2 mL and mean operative time was 82.1 min. No severe intraoperative and postoperative complications were presented. 121 of the studied women had pregnancy 3-36 months after myomectomy, without reporting any uterine rupture. When comparing LIM vs. LAIM, all outcomes were also favorable in the total of patients.
Intracapsular myomectomy either by LIM or LAIM is a safe and attractive alternative to abdominal myomectomy in setting of premenopausal patients with myomas up to 14 cm. A single-layer continuous suturing in intracapsular myomectomies is enough for a successful wound healing.
评估囊内单层子宫肌瘤切除术的疗效和安全性,并根据手术方式的不同观察潜在的变化。
这是一项前瞻性观察研究,于 2010 年 1 月至 2018 年 12 月进行。纳入年龄在生育期、患有 4-14cm 直径的壁间或浆膜下子宫肌瘤(FIGO 3-6 型)的女性。主要结局包括子宫初始和最终切口长度、伤口愈合时间以及后续妊娠中的子宫破裂。此外,还针对手术方式(即腹腔镜或腹腔镜辅助子宫肌瘤切除术)进行了亚分析,以确认这两种潜在手术方式的总体观察结果是否相似。
最终有 273 例患者纳入本研究。总体而言,子宫初始切口平均为 3.1cm,手术结束时缩短至 2.2cm,减少了 29.1%。平均估计出血量为 154.2mL,平均手术时间为 82.1min。术中及术后无严重并发症。273 例患者中有 121 例在子宫肌瘤切除术后 3-36 个月怀孕,未报告任何子宫破裂。比较 LIM 与 LAIM,所有结局在所有患者中均是有利的。
对于有子宫肌瘤的绝经前患者,子宫肌瘤切除术(无论 LIM 或 LAIM)是一种安全且有吸引力的替代剖腹手术的方法,最大可达 14cm。囊内子宫肌瘤切除术的单层连续缝合足以实现成功的伤口愈合。