Kartal Kosuyolu Training and Research Hospital, Cardiology Clinic, Istanbul, Turkey.
Umraniye Training and Research Hospital, Cardiology Clinic, Istanbul, Turkey.
Acta Cardiol. 2021 Aug;76(6):605-610. doi: 10.1080/00015385.2020.1751958. Epub 2020 Apr 14.
The aim of present study is to evaluate the predictive value of QTc dispersion, Tp-Te interval and Tp-Te/QT ratio for idiopathic monomorphic outflow tract ventricular tachycardia (VT) occurrence in patients with frequent idiopathic outflow tract premature ventricular complexes (PVCs).
A total of 180 patients (49.2 ± 13.6 years, 74 male) who had undergone outflow tract PVC ablation between 01 January 2015 and 01 November 2018 constituted our study population. Patients with isolated outflow tract PVC without any VT recording on Holter recordings and without any inducible VT at EPS were classified as isolated PVC group. Patients with any episode of VT that has the same morphology with outflow tract PVC were classified as nonsustained or sustained VT groups based on the duration of VT episode. QTc dispersion, Tp-Te and Tp-Te/QT ratio values were calculated and compared between groups.
There were 116 patients with isolated PVC, 35 patients with nonsustained VT and 29 patients with sustained VT. QTc dispersion, Tp-Te and Tp-Te/QT ratio values were significantly lower in patients with isolated PVC compared to patients with nonsustained or sustained VT episodes. Tpeak to Tend interval greater than 110.5 msec on derivation V6 predicted VT occurrence with 93.8% sensitivity and 82.8% specificity. Tpeak to Tend/QT interval greater than 0.27 on derivation V6 predicted VT occurrence with 93.8% sensitivity and 0.81% specificity.
Tp-Te interval and Tp-Te/QT ratio on derivation V6 may aid in prediction of presence of outflow tract VT in clinical practice.
本研究旨在评估 QT 离散度、Tp-Te 间期和 Tp-Te/QT 比值对频发特发性流出道室性早搏(PVC)患者特发性单形性流出道室性心动过速(VT)发生的预测价值。
本研究共纳入 180 例患者(49.2±13.6 岁,男性 74 例),这些患者于 2015 年 1 月 1 日至 2018 年 11 月 1 日期间行流出道 PVC 消融术。根据 Holter 记录和 EPS 检查,将无任何 VT 记录且无诱发性 VT 的孤立性流出道 PVC 患者分为孤立性 PVC 组,将有任何与流出道 PVC 形态相同的 VT 发作的患者分为非持续性或持续性 VT 组。比较各组间 QT 离散度、Tp-Te 和 Tp-Te/QT 比值。
孤立性 PVC 患者 116 例,非持续性 VT 患者 35 例,持续性 VT 患者 29 例。与非持续性或持续性 VT 组患者相比,孤立性 PVC 患者的 QT 离散度、Tp-Te 和 Tp-Te/QT 比值明显更低。V6 导联 Tpeak 至 Tend 间期大于 110.5 msec 预测 VT 发生的敏感性为 93.8%,特异性为 82.8%。V6 导联 Tpeak 至 Tend/QT 间期大于 0.27 预测 VT 发生的敏感性为 93.8%,特异性为 0.81%。
V6 导联 Tp-Te 间期和 Tp-Te/QT 比值可能有助于预测临床实践中流出道 VT 的存在。