家族性和散发性多发性硬化症的人口统计学和临床特征：阿布扎比单中心探索性研究。
Demographic and clinical characteristics of familial and sporadic multiple sclerosis: A single center exploratory study from Abu Dhabi.
机构信息
Neurological Institute, Cleveland Clinic Abu Dhabi, Sowwah Square, Al Maryah Island, PO Box 112412, Abu Dhabi, United Arab Emirates.
Neurological Institute, Cleveland Clinic Abu Dhabi, Sowwah Square, Al Maryah Island, PO Box 112412, Abu Dhabi, United Arab Emirates.
出版信息
J Clin Neurosci. 2020 Jun;76:145-147. doi: 10.1016/j.jocn.2020.04.007. Epub 2020 Apr 10.
Demographic and clinical characteristics of Familial Multiple Sclerosis (FMS) have not been fully investigated yet in Abu Dhabi. The aim of this single center exploratory study was to investigate demographic and clinical characteristics of FMS compared to sporadic MS (SMS) in Abu Dhabi. A chart review single center study was conducted in 98 patients with MS. Group comparisons were performed using Mann-Whitney and Chi-Square tests as appropriate. A p < 0.05 was considered statistically significant. 24.5% were patients with FMS and 83% were Emirates. No significant differences in demographic and clinical characteristics were found between patients with FMS and SMS in overall all MS patients and in the Emirati group analyzed alone. Patients with FMS did not differ in demographic and clinical characteristics compared to patients with SMS. Further prospective studies are needed to elucidate environmental and genetic risk factors contributing to FMS in the Emirati population.
在阿布扎比，家族性多发性硬化症（FMS）的人口统计学和临床特征尚未得到充分研究。本单中心探索性研究的目的是调查 FMS 与阿布扎比散发型多发性硬化症（SMS）的人口统计学和临床特征。对 98 例 MS 患者进行了图表回顾性单中心研究。使用 Mann-Whitney 和 Chi-Square 检验进行组间比较，p<0.05 被认为具有统计学意义。24.5%的患者为 FMS 患者，83%为阿联酋人。总体所有 MS 患者和单独分析的阿联酋人组中，FMS 患者与 SMS 患者在人口统计学和临床特征方面无显著差异。FMS 患者与 SMS 患者在人口统计学和临床特征方面无差异。需要进一步的前瞻性研究来阐明导致阿联酋人 FMS 的环境和遗传危险因素。
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