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乳房手术后阿片类药物的使用量随着简短的教育干预而减少:一项随机对照试验。

Opioid Consumption Following Breast Surgery Decreases with a Brief Educational Intervention: A Randomized, Controlled Trial.

机构信息

Department of Plastic Surgery, University of Kansas Medical Center, Kansas City, KS, USA.

Department of Psychiatry and Behavioral Sciences, University of Kansas Medical Center, Kansas City, KS, USA.

出版信息

Ann Surg Oncol. 2020 Sep;27(9):3156-3162. doi: 10.1245/s10434-020-08432-7. Epub 2020 Apr 13.

Abstract

BACKGROUND

Current rates of opioid prescribing and consumption in the United States have resulted in deleterious consequences for both patients and society. There has been a focus on opioid consumption and overprescribing, but the utility of patient education in reducing opioid consumption has only recently been explored. This randomized trial aimed to evaluate the effectiveness of a brief patient educational intervention in reducing pain and opioid consumption in patients undergoing mastectomy and breast reconstruction.

METHODS

A parallel, randomized, single-center trial of women undergoing mastectomy with immediate, implant-based breast reconstruction was completed to evaluate the utility of a patient educational instrument with information on multi-modal pain control. A questionnaire was administered postoperatively to collect data on pain control and opioid consumption.

RESULTS

Fifty participants were randomized to each group preoperatively; 46 control (92%) and 39 intervention (78%) participants completed the postoperative questionnaire. Active tobacco use was more common in the control group (p = 0.04). There was a trend towards lower pain scores in the intervention group (3.0/10, SD 1.8 vs 3.6/10, SD 1.6, p = 0.06). Both groups were prescribed a median of 32.0 5-mg oxycodone tablets postoperatively. Participants in the intervention group consumed 33% fewer opioids than the control group (16.2 tablets, SD 16.4 vs 24.3 tablets, SD 21.8, p = 0.05).

CONCLUSIONS

The use of a brief educational intervention provided at a preoperative appointment can reduce opioid consumption. We recommend the use of an educational intervention to decrease opioid consumption among breast surgery patients.

摘要

背景

目前美国的阿片类药物处方和使用量导致患者和社会都受到了不良影响。人们一直关注阿片类药物的使用和过度处方问题,但最近才开始探索患者教育在减少阿片类药物使用方面的作用。这项随机试验旨在评估简短的患者教育干预在减少接受乳房切除术和乳房重建的患者的疼痛和阿片类药物使用方面的有效性。

方法

完成了一项针对接受即刻、植入物为基础的乳房重建的乳房切除术的女性的平行、随机、单中心试验,以评估具有多模式疼痛控制信息的患者教育工具的效用。术后通过问卷调查收集疼痛控制和阿片类药物使用的数据。

结果

50 名参与者在术前随机分配到每组;46 名对照组(92%)和 39 名干预组(78%)参与者完成了术后问卷调查。对照组中主动吸烟更为常见(p=0.04)。干预组的疼痛评分有较低的趋势(3.0/10,SD 1.8 与 3.6/10,SD 1.6,p=0.06)。两组术后均开具了中位数为 32.0 片 5 毫克羟考酮片剂。与对照组相比,干预组的阿片类药物消耗量减少了 33%(16.2 片,SD 16.4 与 24.3 片,SD 21.8,p=0.05)。

结论

在术前预约时使用简短的教育干预可以减少阿片类药物的使用。我们建议使用教育干预来减少乳房手术患者的阿片类药物使用。

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