Malo-Urriés Miguel, Estébanez-de-Miguel Elena, Bueno-Gracia Elena, Tricás-Moreno José Miguel, Santos-Lasaosa Sonia, Hidalgo-García César
Physiotherapy Research Unit, Department of Psychiatry and Nursing, University of Zaragoza, Zaragoza, Spain.
Facultad de Ciencias de la Salud, Universidad de Zaragoza, c/ Domingo Miral s/n, 50009, Zaragoza, Spain.
Neurol Sci. 2020 Oct;41(10):2801-2810. doi: 10.1007/s10072-020-04384-8. Epub 2020 Apr 13.
Studies evaluating sensory function of the entire trigeminocervical region in patients with cluster headache (CH), migraine (MH), and tension-type headache (TH) are required. The purpose of the present study was to evaluate and compare sensory function in the trigeminocervical region in patients with CH, MH, and TH and healthy controls (HC).
Quantitative sensory testing (QST), including pressure pain threshold (PPT), tactile detection threshold (TDT), prick detection threshold (PDT), and two-point detection threshold (2PDT), was evaluated in 139 patients with headache (CH = 16, MH = 52, TH = 71) and 30 HC. Test sites included bilaterally the first, second, and third divisions of trigeminal nerve (V1, V2, and V3), cervical spine, and thenar eminence.
TH presented significantly lower PPT values compared with CH (p < 0.015), MH (p < 0.048), and HC (p < 0.009), while MH demonstrated significantly lower values than HC (p = 0.001-0.023). When analyzing TDT, CH in the symptomatic side presented significantly higher values in V1 compared with MH (p = 0.001), TH (p < 0.001), and HC (p < 0.001) and in V2 compared with TH (p = 0.035). No statistically significant differences were found for PDT (p > 0.005). With regard to 2PDT, CH-s presented significantly higher values in V1 with respect to HC (p = 0.016) but lower values in V2 compared with MH (p < 0.001) and TH (p = 0.003).
The results of the present study indicate specific and different altered mechanical sensory thresholds in CH, MH, and TH patients compared with HC subjects.
需要开展研究评估丛集性头痛（CH）、偏头痛（MH）和紧张型头痛（TH）患者整个三叉神经颈区域的感觉功能。本研究的目的是评估和比较CH、MH、TH患者以及健康对照者（HC）三叉神经颈区域的感觉功能。
对139例头痛患者（CH = 16例，MH = 52例，TH = 71例）和30例HC进行定量感觉测试（QST），包括压痛阈值（PPT）、触觉检测阈值（TDT）、针刺检测阈值（PDT）和两点检测阈值（2PDT）。测试部位包括双侧三叉神经的第一、第二和第三分支（V1、V2和V3）、颈椎和鱼际隆起。
与CH（p < 0.015）、MH（p < 0.048）和HC（p < 0.009）相比，TH的PPT值显著更低，而MH的值显著低于HC（p = 0.001 - 0.023）。在分析TDT时，有症状一侧的CH在V1中的值显著高于MH（p = 0.001）、TH（p < 0.001）和HC（p < 0.001），在V2中高于TH（p = 0.035）。PDT未发现统计学显著差异（p > 0.005）。关于2PDT，有症状的CH在V1中的值相对于HC显著更高（p = 0.016），但在V2中相对于MH（p < 0.001）和TH（p = 0.003）更低。
本研究结果表明，与HC受试者相比，CH、MH和TH患者的机械感觉阈值存在特定且不同的改变。
