丛集性头痛的感觉功能：一项比较有症状侧和无症状侧的观察性研究。

Sensory function in cluster headache: an observational study comparing the symptomatic and asymptomatic sides.

作者信息

Malo-Urriés Miguel, Hidalgo-García César, Estébanez-de-Miguel Elena, Tricás-Moreno José Miguel, Santos-Lasaosa Sonia, Jahanshahi Marjan

机构信息

Physiotherapy Research Unit, Department of Physiatry and Nursing, University of Zaragoza, Zaragoza, Spain,

Neurology Service, University Clinical Hospital Lozano Blesa, Zaragoza, Spain.

出版信息

Neuropsychiatr Dis Treat. 2018 Dec 10;14:3363-3371. doi: 10.2147/NDT.S186051. eCollection 2018.

DOI:10.2147/NDT.S186051

PMID:30573960

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6292232/

Abstract

BACKGROUND

Based on inconsistent sensory alterations demonstrated in cluster headache (CH), the aim of this study was to determine whether patients with CH develop sensory changes in the symptomatic side compared to the asymptomatic side.

METHODS

Quantitative sensory testing (QST), including pressure pain threshold (PPT), tactile detection threshold (TDT), prick detection threshold (PDT), and two-point detection threshold (2PDT), was evaluated in 16 patients (seven women; age 41.9±6.8 years) with CH. Test sites included the first, second, and third divisions of the trigeminal nerve, cervical spine, and thenar eminence in the symptomatic and asymptomatic sides.

RESULTS

The symptomatic side, compared to the asymptomatic side, presented significantly decreased PPT in the first (=0.011; 423.81±174.05 kPa vs 480.13±214.99 kPa) and second (=0.023; 288.88±140.80 kPa vs 326.38±137.33 kPa) divisions of the trigeminal nerve, significantly increased TDT in the first (=0.002; 2.44±0.40 vs 1.74±0.24) and second (=0.016; 1.92±0.34 vs 1.67±0.09) divisions, and increased 2PDT in the first division (=0.004; 18.13±4.70 mm vs 15.0±4.92 mm) and neck (=0.007; 45.31±20.65 mm vs 38.44±16.10 mm).

CONCLUSION

These results support the prior evidence suggesting a specific pattern of alteration of sensory function with alterations in the symptomatic side compared to the asymptomatic side.

摘要

背景

基于丛集性头痛（CH）中所显示的不一致的感觉改变，本研究的目的是确定与无症状侧相比，CH患者在症状侧是否出现感觉变化。

方法

对16例CH患者（7例女性；年龄41.9±6.8岁）进行了定量感觉测试（QST），包括压痛阈值（PPT）、触觉检测阈值（TDT）、针刺检测阈值（PDT）和两点检测阈值（2PDT）。测试部位包括三叉神经的第一、第二和第三分支、颈椎以及症状侧和无症状侧的鱼际隆起。

结果

与无症状侧相比，症状侧三叉神经第一分支（=0.011；423.81±174.05千帕对480.13±214.99千帕）和第二分支（=0.023；288.88±140.80千帕对326.38±137.33千帕）的PPT显著降低，第一分支（=0.002；2.44±0.40对1.74±0.24）和第二分支（=0.016；1.92±0.34对1.67±0.09）的TDT显著升高，第一分支（=0.004；18.13±4.70毫米对15.0±4.92毫米）和颈部（=0.007；45.31±20.65毫米对38.44±16.10毫米）的2PDT升高。