De Luca Júnior L A, Diniz D L, Antunes-Rodrigues J
Departamento de Fisiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Brasil.
Braz J Med Biol Res. 1988;21(3):573-5.
The effect of atropine injection into the medial septal area (MSA) or medial preoptic area (MPOA) on carbachol-induced drinking was evaluated in conscious unrestrained rats during a food-associated drinking test reinforced by 14 h of food deprivation. Atropine did not alter food intake when injected into either area, nor did it affect drinking after its injection into the MPOA. However, atropine markedly reduced water intake after its injection into the MSA. These results suggest that the central cholinergic system in the MSA can participate in the regulation of food-associated drinking.
在通过14小时食物剥夺强化的食物相关饮水测试中，评估了向内侧隔区（MSA）或内侧视前区（MPOA）注射阿托品对卡巴胆碱诱导饮水的影响。在清醒自由活动的大鼠中进行该实验。向任一区域注射阿托品均未改变食物摄入量，向MPOA注射后也不影响饮水。然而，向MSA注射阿托品后显著减少了水的摄入量。这些结果表明，MSA中的中枢胆碱能系统可参与食物相关饮水的调节。
