Beijing Key Laboratory for Separation and Analysis in Biomedicine and Pharmaceutical, Beijing Institute of Technology, (BIT), Beijing 100081, PR China; Faculty of Marine Sciences, the Lasbela University of Agriculture, Water and Marine Sciences, (LUAWMS), Uthal, Balochistan, Pakistan.
School of Pharmacy, Nanjing Medical University, Jiangsu Province, Nanjing 211166, PR China.
Int J Biol Macromol. 2020 Aug 1;156:420-429. doi: 10.1016/j.ijbiomac.2020.04.022. Epub 2020 Apr 11.
Cyclocarya paliurus is essential and only living specie of the genus Cyclocarya Iljinskaja. The leaves of this plant have been extensively used as food in the form of tea and green vegetable. Many compounds have been isolated from this plant, and their useful aspects explored, including the polysaccharides. Studies conducted on leaves show that different methods of extraction have been used, as well as a combination of different techniques that have been applied to isolate polysaccharides from the leaves. Their structure has been elucidated because the activity of polysaccharides mainly depends upon their composition. It has been reported that different activities exhibited by the isolated crude, purified as well as modified polysaccharides include, anticancer, anti-inflammatory, antioxidant, antimicrobial, anti-hyperlipidemic and anti-diabetic activities. In some studies, a comparison of crude extract, as well as purified polysaccharide, has been performed. In this review, we have summarized all the available literature available on the methods of extraction, structure, and biological activities of polysaccharides from the leaves of C. paliurus and indicated the potential research areas that should be focused on future studies. We believe that this review will provide an up to date knowledge regarding polysaccharides of C. paliurus for the researchers.
青钱柳是青钱柳属中唯一现存的种。这种植物的叶子被广泛用作茶和绿色蔬菜的形式。已经从这种植物中分离出许多化合物，并探索了它们的有用方面，包括多糖。对叶子的研究表明，已经使用了不同的提取方法，以及将不同技术结合起来从叶子中分离多糖的方法。已经阐明了它们的结构，因为多糖的活性主要取决于它们的组成。据报道，从分离的粗提物、纯化的以及修饰的多糖中表现出的不同活性包括抗癌、抗炎、抗氧化、抗菌、抗高血脂和抗糖尿病活性。在一些研究中，对粗提取物以及纯化的多糖进行了比较。在这篇综述中，我们总结了关于青钱柳叶子多糖的提取方法、结构和生物活性的所有现有文献，并指出了未来研究应关注的潜在研究领域。我们相信，这篇综述将为研究人员提供关于青钱柳多糖的最新知识。
