School of Health and Environmental Science, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.
Department of Health Science, Korea University, 145 Anam-ro, Seongbuk-gu, Seoul 02841, Korea.
Int J Environ Res Public Health. 2020 Apr 10;17(7):2611. doi: 10.3390/ijerph17072611.
Some beverages and smoking cause an inflammatory response in the lungs and airways in a similar way, ultimately affecting chronic obstructive pulmonary disease (COPD) occurrence. Using a nationally representative health survey database, this study investigates the individual and joint effects of consumption of different beverages and smoking on COPD. This study is a cross-sectional analysis of 15,961 Korean adults in the Korea National Health and Nutritional Examination Survey of 2008-2015. COPD was defined as forced expiratory volume in 1 s (FEV) divided by forced vital capacity (FVC) <0.70. We used multiple linear and logistic regression models to examine the association of beverage consumption and smoking with an FEV/FVC ratio and odds ratio (OR) for COPD. The mean FEV/FVC ratio decreased with increasing soda intake ( = 0.016), coffee intake ( = 0.031), and smoking status; however, the mean FEV/FVC ratio increased with increasing green tea intake frequency ( = 0.029). When soda intake increased to 10 times/month, the OR of having COPD increased to 1.04 times (95% CI: 1.01, 1.07). The positive joint effect of soda intake and smoking on COPD was marginally significant ( = 0.058). We found that soda intake, coffee intake, and smoking increased airflow limitation while green tea intake decreased it. In addition, soda intake and smoking had a positive joint effect on COPD in the Korean population.
一些饮料和吸烟以类似的方式引起肺部和气道的炎症反应，最终影响慢性阻塞性肺疾病（COPD）的发生。本研究利用全国代表性健康调查数据库，调查了不同饮料的摄入和吸烟对 COPD 的单独和联合影响。这是对 2008-2015 年韩国全国健康和营养检查调查中 15961 名韩国成年人进行的横断面分析。COPD 定义为 1 秒用力呼气量（FEV）与用力肺活量（FVC）之比<0.70。我们使用多元线性和逻辑回归模型来检查饮料消费和吸烟与 FEV/FVC 比值以及 COPD 的比值比（OR）的关联。随着苏打水摄入量（ = 0.016）、咖啡摄入量（ = 0.031）和吸烟状态的增加，平均 FEV/FVC 比值降低；然而，随着绿茶摄入频率的增加（ = 0.029），平均 FEV/FVC 比值增加。当苏打水摄入量增加到每月 10 次时，COPD 的 OR 增加到 1.04 倍（95%CI：1.01，1.07）。苏打水摄入量和吸烟对 COPD 的阳性联合效应具有边缘显著性（ = 0.058）。我们发现，苏打水摄入、咖啡摄入和吸烟增加了气流受限，而绿茶摄入则降低了气流受限。此外，苏打水摄入和吸烟对韩国人群中的 COPD 有积极的联合效应。
