Hong Ji Young, Jung Ji Ye, Lee Myung Goo, Kim Se Kyu, Chang Joon, Lee Chang Youl, Kim Young Sam
Division of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Chuncheon Sacred Heart Hospital, Hallym University Medical Center, Chuncheon, Gangwon-do, Republic of Korea; Lung Research Institute of Hallym University College of Medicine, Chuncheon, Gangwon-do, Republic of Korea.
Division of Pulmonology, Department of Internal Medicine, Yonsei University College of Medicine, 50 Yonseiro, Seodaemun-gu, Seoul 120-752, Republic of Korea.
Respir Med. 2017 Apr;125:12-18. doi: 10.1016/j.rmed.2017.02.019. Epub 2017 Feb 27.
Chronic obstructive pulmonary disease (COPD) is a serious public health problem. Understanding the longitudinal trend in prevalence is important for characterizing the burden of COPD and planning health services.
We analyzed the prevalence of airflow obstruction between 2001 and 2011 using data from Korean National Health and Nutritional Examination Surveys (2001, n = 2217; 2011, n = 3101). Participants >40 years of age with an FEV/FVC <0.7 were defined as having COPD. We used data from the Population and Housing Census, which was conducted by Statistics Korea in 2010, to compare the prevalence of COPD after standardizing by age.
The crude prevalence of COPD was not significantly different between 2001 and 2011 (2001, 13.0%; 2011, 13.2%), but the age-standardized prevalence of COPD decreased significantly over the 10-year period (2001, 15.7%; 2011, 12.4%). While significant decreases were observed for ex-smokers and current smokers, significant increases were noted for subjects who smoked <20 pack-years and those with a BMI ≤18.5 kg/m. The prevalence of mild and severe COPD decreased (2001, mild 8.5%, severe 1.4%; 2011, mild 5.4%, severe 0.5%), while the prevalence of moderate COPD increased (2001, 5.7%; 2011, 6.4%) after age standardization.
We report a reduction in the age-standardized prevalence of COPD in Korea from 2001 to 2011. Continued surveillance and early prevention are required because the socioeconomic burden of COPD remains substantial.
慢性阻塞性肺疾病（COPD）是一个严重的公共卫生问题。了解患病率的纵向趋势对于描述COPD的负担和规划卫生服务至关重要。
我们使用韩国国家健康与营养检查调查（2001年，n = 2217；2011年，n = 3101）的数据，分析了2001年至2011年期间气流受限的患病率。FEV/FVC<0.7的40岁以上参与者被定义为患有COPD。我们使用韩国统计厅2010年进行的人口与住房普查数据，按年龄标准化后比较COPD的患病率。
2001年至2011年期间，COPD的粗患病率无显著差异（2001年为13.0%；2011年为13.2%），但COPD的年龄标准化患病率在这10年期间显著下降（2001年为15.7%；2011年为12.4%）。虽然前吸烟者和当前吸烟者的患病率显著下降，但吸烟<20包年的人群和BMI≤18.5 kg/m的人群患病率显著上升。年龄标准化后，轻度和重度COPD的患病率下降（2001年，轻度8.5%，重度1.4%；2011年，轻度5.4%，重度0.5%），而中度COPD的患病率上升（2001年为5.7%；2011年为6.4%）。
我们报告了2001年至2011年韩国COPD年龄标准化患病率的下降。由于COPD的社会经济负担仍然很大，需要持续监测和早期预防。
