Anti-IL6R role in treatment of COVID-19-related ARDS.
作者信息
Buonaguro Franco Maria, Puzanov Igor, Ascierto Paolo Antonio
机构信息
Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione "G. Pascale", Via Mariano Semmola, 80131, Naples, Italy.
Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
出版信息
J Transl Med. 2020 Apr 14;18(1):165. doi: 10.1186/s12967-020-02333-9.
Abstract
摘要
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本文引用的文献
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Why tocilizumab could be an effective treatment for severe COVID-19?为什么托珠单抗可能是治疗严重 COVID-19 的有效方法？
J Transl Med. 2020 Apr 14;18(1):164. doi: 10.1186/s12967-020-02339-3.
2
Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection.抗刺突 IgG 通过在急性 SARS-CoV 感染期间使巨噬细胞反应发生偏斜，导致严重的急性肺损伤。
JCI Insight. 2019 Feb 21;4(4). doi: 10.1172/jci.insight.123158.
3
Interleukin-6 limits influenza-induced inflammation and protects against fatal lung pathology.白细胞介素-6 限制流感引起的炎症并防止致命的肺部病理。
Eur J Immunol. 2013 Oct;43(10):2613-25. doi: 10.1002/eji.201243018. Epub 2013 Aug 12.
4
Impact of tocilizumab therapy on antibody response to influenza vaccine in patients with rheumatoid arthritis.托珠单抗治疗对类风湿关节炎患者流感疫苗抗体应答的影响。
Ann Rheum Dis. 2012 Dec;71(12):2006-10. doi: 10.1136/annrheumdis-2012-201950. Epub 2012 Aug 11.
5
Essential role of IL-6 in protection against H1N1 influenza virus by promoting neutrophil survival in the lung.IL-6 在保护肺部免受 H1N1 流感病毒感染中的重要作用：促进中性粒细胞存活。
Mucosal Immunol. 2012 May;5(3):258-66. doi: 10.1038/mi.2012.2. Epub 2012 Feb 1.
6
Interleukin-6 is crucial for recall of influenza-specific memory CD4 T cells.白细胞介素-6对于流感特异性记忆CD4 T细胞的回忆至关重要。
PLoS Pathog. 2008 Feb 29;4(2):e1000006. doi: 10.1371/journal.ppat.1000006.
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