Bröms Gabriella, Cahling Lindah, Berntsson Anders, Öhrmalm Lars
Unit of Clinical Epidemiology, Centre for Pharmacoepidemiology, Karolinska Institutet, Stockholm, Sweden.
PRIMA Child and Adult Psychiatry, Stockholm, Sweden.
BJPsych Bull. 2020 Dec;44(6):265-268. doi: 10.1192/bjb.2020.28.
To assess whether the combination of motivational interviewing and psychoeducation affects relapse rate and stimulates involvement of people with psychosis in their treatment. We conducted an interventional study including patients with schizophrenia or schizoaffective disorder treated with oral antipsychotics, without previous experience of long-acting injectable antipsychotics (LAIs). They were randomised to either psychoeducation with motivational interviewing or a control group. Hospital admissions 18 months before and after the intervention, and switches to LAIs 18 months after the intervention, were recorded.
The two groups each comprised 101 participants. Fourteen from the intervention group and seven from the control group switched to LAIs. Five in the intervention group instigated the switch themselves, compared with zero controls (P = 0.06). Fourteen in the intervention group were readmitted to hospital during follow-up, compared with 23 in the control group (P = 0.14).
Psychoeducation with motivational interviewing may increase patients' involvement in their treatment and reduce the relapse frequency.
评估动机性访谈与心理教育相结合是否会影响复发率，并促进精神病患者参与其治疗。我们进行了一项干预性研究，纳入了使用口服抗精神病药物治疗的精神分裂症或分裂情感性障碍患者，这些患者既往没有长效注射用抗精神病药物（LAIs）治疗经验。他们被随机分为接受动机性访谈心理教育组或对照组。记录干预前后18个月的住院情况，以及干预后18个月转为使用LAIs的情况。
两组各有101名参与者。干预组有14人、对照组有7人转为使用LAIs。干预组有5人自行促成了这种转变，而对照组为零（P = 0.06）。随访期间，干预组有14人再次住院，对照组有23人（P = 0.14）。
动机性访谈心理教育可能会增加患者对治疗的参与度，并降低复发频率。
