单核细胞和淋巴细胞诱导的玻璃体纤维化的细胞密度依赖性

Cell density dependency of vitreous fibrosis induced by monocytes and lymphocytes.

作者信息

Raymond L A, Katakami C, Lipman M J, Alexander D W, Spaulding A G, Choromokos E, Kao W W

机构信息

Department of Ophthalmology, University of Cincinnati College of Medicine, OH 45267.

出版信息

Curr Eye Res. 1988 Dec;7(12):1191-7. doi: 10.3109/02713688809033223.

DOI:10.3109/02713688809033223

PMID:3229130

Abstract

The possible roles of monocytes and lymphocytes in vitreous fibrosis were examined by injecting various numbers of the peripheral cell types into the rabbit vitreous. Our results indicated that the degree of vitreous fibrosis and the presence of traction retinal detachment corresponded to the number of cells injected. It was suggested that these findings are probably similar to vitreous membrane formation and retinal detachment in various clinical ocular diseases or inflammations in humans.

摘要

通过向兔玻璃体注射不同数量的外周细胞类型，研究了单核细胞和淋巴细胞在玻璃体纤维化中的可能作用。我们的结果表明，玻璃体纤维化程度和牵拉性视网膜脱离的存在与注射的细胞数量相对应。提示这些发现可能与人类各种临床眼病或炎症中的玻璃体膜形成和视网膜脱离相似。