Liao Jiayu, Way George, Madahar Vipul
Department of Bioengineering, Bourns College of Engineering, University of California at Riverside, 900 University Avenue, Riverside, California 92521.
Med Drug Discov. 2020 Mar;5:100037. doi: 10.1016/j.medidd.2020.100037. Epub 2020 Apr 13.
The COVID-19 pandemic, after it was reported in December 2019, is a highly contagious and now spreading to over 190 countries, causing a severe public health burden. Currently, there is no vaccine or specific drug to treat COVID-19, which is caused by a novel coronavirus, SARS-2-CoV. For this emergency, the FDA has approved Remdesivir and Hydroxychloroquine for treatment of COVID-19 as Emergency Use Authorization. However, even after this pandemic, COVID-19 may still have a chance to come back. Therefore, we need to come out with new strategies for drug discovery for combating COVID-19 in the future.
2019年12月新冠疫情被报道后，它具有高度传染性，目前已蔓延至190多个国家，造成了严重的公共卫生负担。目前，尚无疫苗或特定药物可治疗由新型冠状病毒SARS-CoV-2引起的新冠疫情。针对这一紧急情况，美国食品药品监督管理局（FDA）已批准瑞德西韦和羟氯喹作为紧急使用授权用于治疗新冠疫情。然而，即使在这场疫情之后，新冠疫情仍有可能卷土重来。因此，我们需要想出新的药物研发策略，以便在未来抗击新冠疫情。
