Müller C, Cernin J, Glogar D, Laczkovics A, Mayr H, Scheibelhofer W, Schmidinger H, Schuster E, Sedlacek K, Kaliman J
Department of Cardiology, University of Vienna, Austria.
Eur Heart J. 1988 Sep;9(9):1003-9. doi: 10.1093/oxfordjournals.eurheartj.a062591.
The survival rate of 2256 patients with pacemakers was analyzed. Patients paced for Adams-Stokes equivalents (e.g. dizziness) showed a significantly better survival rate than did patients with pacemakers implanted for Adam-Stokes attacks or heart failure (P less than 0.0001). The estimated survival of the latter two groups did not differ significantly. Of the deceased patients who had received a pacemaker for the treatment of heart failure, 54% died due to this condition despite pacemaker implantation. The relative percentage of cases of sudden death after pacemaker implantation was high in the groups with Adams-Stokes attacks (12%) and Adams-Stokes equivalents (13%). In patients paced for Adams-Stokes attacks, sudden death occurred more frequently in the first year after pacemaker implantation (P less than 0.015) than during the following years. Therefore, increased efforts should be made to monitor patients carefully after pacemaker implantation to enable prompt detection of malignant tachyarrhythmias, probably the cause of sudden death in a substantial number of patients with pacemakers.
对2256例植入起搏器的患者的生存率进行了分析。因阿-斯综合征等效症状（如头晕）而植入起搏器的患者，其生存率显著高于因阿-斯综合征发作或心力衰竭而植入起搏器的患者（P<0.0001）。后两组的估计生存率无显著差异。在因心力衰竭接受起搏器治疗的死亡患者中，尽管植入了起搏器，但54%死于该疾病。在因阿-斯综合征发作和阿-斯综合征等效症状而植入起搏器的组中，起搏器植入后猝死的相对比例较高（分别为12%和13%）。在因阿-斯综合征发作而植入起搏器的患者中，起搏器植入后的第一年猝死发生率高于随后几年（P<0.015）。因此，应加大力度在起搏器植入后仔细监测患者，以便及时发现恶性快速心律失常，这可能是大量起搏器患者猝死的原因。
